Gene Expression and Molecular Cloning > Genetic Engineering Services Products & Reviews

Human iPSC-derived glutamatergic neurons expressing Cas9 for rapid gene knockout generation

Genotyping by sequencing (GBS) is the cost-effective method of choice for genome-wide SNP discovery without prior knowledge of the genome sequence.

The LightCycler® 96 Instrument is a real-time PCR instrument for rapid cycling up to 96 samples. Applications include absolute and relative quantification, melting curve analysis, and endpoint genotyping. Precise LightCycler® 96 Instrument thermal homogeneity and cycling speed produce accurate and reproducible results in a very short time. The LightCycler® 96 Instrument’s optical detection system flexibly detects sequenc…

C. elegans transgenics built to your specs

Human iPSC-derived microglia expressing Cas9 for rapid gene knockout generation

Creative Biolabs delivers an end-to-end CAR-T development pathway—from target/scFv discovery, CAR design and vectoring, and cell engineering to in-vitro/in-vivo efficacy, IND authoring, and manufacturing support. Modular and GMP-aligned, the platform spans autologous and allogeneic routes (incl. TRAC/Cas9 and mRNA) to de-risk translation for hematologic and solid tumor programs.

End‑to‑end TCR‑like antibody services targeting peptide–MHC complexes—covering immunogen design, pMHC screening, affinity maturation, developability optimization, and functional validation—with output as IgG, bispecifics, or CAR constructs to access intracellular‑derived antigens.

End‑to‑end solid‑tumor CAR‑T development—from antigen/scFv discovery and CAR optimization to cell engineering, in‑vitro/in‑vivo efficacy, and IND support. Incorporates dual/logic‑gated and armored CARs, plus trafficking and persistence enhancements to overcome the tumor microenvironment and improve safety and translation.

End‑to‑end allogeneic cell therapy development—covering donor strategy, multiplex genome editing for safety/immune evasion, scalable manufacturing and comparability, and IND/CMC support—across CAR‑T/CAR‑NK and other donor‑derived modalities to enable off‑the‑shelf access.

Configurable TIL therapy development spanning tumor processing, TIL isolation/rapid expansion, functional and phenotypic qualification, and release criteria—paired with manufacturing‑aligned process development and IND documentation to de‑risk scale‑up for solid‑tumor programs.

OneTRAC™ allows you to profile every gene, validate biomarker signatures, and apply your findings across all your studies. One-stop service for all your gene expression profiling needs All-inclusive gene expression data for pattern recognition and pathway analyses at the macro- and micro-levels Streamlined and integrated methodology from screening to validation of gene signatures Cost-efficient expression profiling f…

GeneCopoeia offers complete custom services for CRISPR-Cas9-based targeted genomic modification, including CRISPR design and construction, donor design and construction, functional validations, stable cell line establishment, and transgenic mouse generation. Service Details: Validation Services Donor clone services Stable cell line services Transgenic mouse services Advantages: Fast delivery of CRISPR-Cas9 plasmids…

Source BioScience are a trusted provider of outsourced services for gene expression projects. Source BioScience work with three major microarray platforms (Affymetrix, Agilent and Illumina) and optimise the most suitable array technology for each project.

Custom cloning services to clone any fragment from the human, mouse or rat genome into any LightSwitch luciferase reporter vector

Custom site-directed mutagenesis services to create any sequence variant from any existing LightSwitch reporter vector

Cell-based screening service to measure the effects of compounds on a variety of biological pathways

Sequence Variant Assay Services to understand the functional impact of sequence variation on promoter or 3´UTR activity

Full screening service to validate the 3´UTR targets of specific miRNAs

Full phenotypic analysis  to connect genes to behavior

Animal models engineered for human disease discovery  

We Inject. You screen.  

Zebrafish transgenics built to your specs

We Inject. You screen.

CRISPR Screening Services Horizon offers comprehensive CRISPR screening services from screen design and cell line selection to sophisticated bioinformatics analysis of the screen results. Our best-in-class CRISPR KO (knockout), CRISPRi (interference) and CRISPRa (activation) screening platforms can significantly advance our customers’ drug development programs by offering the highest quality and highest confidence in their…