High-Throughput Screening Products & Reviews

Recombinant Human Bone Morphogenetic Protein 7 (BMP-7), a TGF-β superfamily member that induces bone and cartilage formation and plays roles in renal development and repair.

Recombinant Human Bone Morphogenetic Protein 2 (BMP-2), a key regulatory protein that induces bone and cartilage formation, used extensively in orthopedics and stem cell differentiation.

Recombinant Human Apolipoprotein E (ApoE), a key protein in lipid metabolism that plays a central role in cardiovascular health and Alzheimer's disease pathogenesis.

A comprehensive collection of active, recombinant protein kinases, crucial for screening and profiling small molecule inhibitors and studying cellular signaling pathways in disease.

Recombinant Human B-cell lymphoma 2 (BCL-2) protein, a key regulator of apoptosis (programmed cell death) and a well-established oncoprotein in many cancers.

Recombinant Human B-cell Antigen Receptor Complex-associated protein alpha chain (CD79A), a essential component of the B-cell receptor (BCR) and a marker for B-cell lineage.

A recombinant B-lymphocyte surface antigen, CD19, which is a pivotal target for immunotherapy in B-cell malignancies, including CAR-T cell and antibody-based therapies.

A wide array of recombinant human and animal cytokines, chemokines, and interferons for studying immune responses, inflammation, hematopoiesis, and cell communication.

Recombinant proteins specifically relevant as E3 ligases or target proteins for Proteolysis Targeting Chimeras (PROTACs), enabling the development of this novel targeted protein degradation technology.

A portfolio of recombinant immunoglobulins and cell surface proteins serving as critical targets for the development and functional validation of Chimeric Antigen Receptor T-cell (CAR-T) therapies.

Recombinant Human Leukocyte Antigen G (HLA-G), a non-classical MHC class I molecule involved in immune tolerance at the maternal-fetal interface and in immune evasion by tumors.

Recombinant Human Fibroblast Growth Factor 2 (Basic FGF), a potent mitogen and morphogen for a wide range of mesoderm and neuroectoderm-derived cells in culture.

Recombinant Human Erythropoietin (EPO), the primary hormone regulating red blood cell production (erythropoiesis), used in research and as a therapeutic for anemia.

Recombinant Human Programmed Cell Death Protein 1 (PD-1/CD279), a critical immune checkpoint receptor that suppresses T-cell activation and is a major target in cancer immunotherapy.

Unleash the full power of a well-designed library. With Twist Bioscience, you are assured that the library you design contains the specific modifications, exactly where you want them, saving you valuable resources for the downstream screening process.

Twist Biopharma, a division of Twist Bioscience, provides services to help accelerate the way our partners discover and optimize antibody therapeutics with our unique DNA writing technology. Twist constructs proprietary antibody libraries precisely designed to match sequences that occur in the human body giving our partners an integral and unbiased resource for antibody therapeutic discovery and optimization.

Twist Biopharma, a division of Twist Bioscience, provides services to help accelerate the way our partners discover and optimize antibody therapeutics with our unique DNA writing technology. Twist constructs proprietary antibody libraries precisely designed to match sequences that occur in the human body giving our partners an integral and unbiased resource for antibody therapeutic discovery and optimization.

The AptaFluor® SAH Methyltransferase Assay Kit enables ultra-sensitive, direct detection of SAH—the universal product of methyltransferase reactions—using a riboswitch-based TR-FRET format. With no coupling enzymes required, it delivers high signal-to-background, Z’ ≥ 0.7, and is fully HTS-compatible for drug discovery and inhibitor screening.

BellBrook Labs’ Lead Discovery Services deliver expert support for hit-to-lead efforts. From inhibitor screening and potency profiling to residence-time, mechanism-of-action, and selectivity studies, their team tailors efficient enzymatic assays to your program—accelerating lead advancement with precision and flexibility.

The Transcreener® cGAMP cGAS Assay Kit offers mix-and-read fluorescent detection of cGAMP—the product of cGAS activity—with no coupling enzymes required. Available in FP or TR‑FRET readouts (far-red tracers minimize interference), it’s HTS-ready (Z’ ≥ 0.7), automation-compatible, and validated on 96‑, 384‑, and 1536‑well formats for enzyme kinetics, SAR, and inhibitor screening.

The CD73 activity assay for HTS and hit-to-lead. Measure specific activity of CD73 in a simple mix-and-read format. The kit is designed for compound library screening and follow-up inhibitor discovery.

The Transcreener dAMP Exonuclease Assay directly measures dAMP produced by exonuclease enzymes as they cleave polynucleotides. 

The Transcreener® GDP GTPase Assay Kit directly measures GDP produced during GTP hydrolysis in a homogeneous mix‑and‑read format—no coupling enzymes needed. Compatible with GTPases, GAPs, and GEFs, it supports FP, FI, and TR‑FRET readouts using far‑red tracers to reduce interference. HTS‑ready with excellent sensitivity (Z′ ≥ 0.7), it streamlines screening and profiling workflows.

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