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HLA-G

Recombinant Human Leukocyte Antigen G (HLA-G), a non-classical MHC class I molecule involved in immune tolerance at the maternal-fetal interface and in immune evasion by tumors.

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HLA-G plays a critical role in suppressing immune responses by inhibiting NK cell and T-cell cytotoxicity. Its expression in cancers and transplants is associated with immune evasion. Our HLA-G protein is essential for studying its immunomodulatory functions and developing diagnostic or therapeutic strategies targeting this pathway.

Key Features & Benefits:

  • Correctly Folded and Glycosylated MHC Complex
  • Binds to ILT-2, ILT-4, and KIR2DL4 Receptors
  • Suitable for Tetramer Formation for T-cell Studies
  • High Purity and Stability

Relevant Applications:

  • Cancer Immunotherapy and Immune Evasion Research
  • Reproductive Immunology and Pregnancy Studies
  • Transplant Tolerance and Rejection Research
  • Therapeutic Antibody Discovery

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