Oligonucleotides Products & Reviews

Optimized primers for different human miRNA that were selected based upon their roles in cancer and development.  Detects mature miRNA  Detects human, mouse, rat, worm and other species  Highly-specific sequences assure single nucleotide discrimination

Optimized primers for different human miRNA that were selected based upon their roles in cancer and development.  Detects mature miRNA  Detects human, mouse, rat, worm and other species  Highly-specific sequences assure single nucleotide discrimination

Optimized primers for different human miRNA that were selected based upon their roles in cancer and development.  Detects mature miRNA  Detects human, mouse, rat, worm and other species  Highly-specific sequences assure single nucleotide discrimination

Optimized primers for different human miRNA that were selected based upon their roles in cancer and development.  Detects mature miRNA  Detects human, mouse, rat, worm and other species  Highly-specific sequences assure single nucleotide discrimination

Optimized primers for different human miRNA that were selected based upon their roles in cancer and development.  Detects mature miRNA  Detects human, mouse, rat, worm and other species  Highly-specific sequences assure single nucleotide discrimination

The Prime-It Fluor fluorescence labeling kit generates directly fluoresceinated DNA probes using random 9-mer primers and Exo-Klenow to incorporate fluor-12-dUTP into the probe fragments.  Generates high-specific-activity probes in 2 minutes  Fluorescently labeled probes also available  Produces labeled fragments 400 bp to 10 kb nucleotides in length  Performs equally well with [32P]dATP and [32P]dCTP  Performs well w…

The Prime-It Fluor fluorescence labeling kit generates directly fluoresceinated DNA probes using random 9-mer primers and Exo-Klenow to incorporate fluor-12-dUTP into the probe fragments.  Generates high-specific-activity probes in 2 minutes  Fluorescently labeled probes also available  Produces labeled fragments 400 bp to 10 kb nucleotides in length  Performs equally well with [32P]dATP and [32P]dCTP  Performs well w…

The Prime-It Fluor fluorescence labeling kit generates directly fluoresceinated DNA probes using random 9-mer primers and Exo-Klenow to incorporate fluor-12-dUTP into the probe fragments.  Generates high-specific-activity probes in 2 minutes  Fluorescently labeled probes also available  Produces labeled fragments 400 bp to 10 kb nucleotides in length  Performs equally well with [32P]dATP and [32P]dCTP  Performs well w…

The Supercoiled DNA Ladder contains fragments from 2 kb to 10 kb at 1-kb increments and an additional band at 12 kb. The Kb DNA Ladder contains fragments from 1 kb to 10 kb at 1-kb increments, as well as bands at 250 bp, 500 bp, 750 bp, 1500 bp and 12 kb.

The universal reverse primer is designed for use with the Human U6 forward primer provided in our High-Specificity miRNA QRT-PCR Detection Kit for a complete, validated assay requiring no upfront design work. The Kit delivers sensitive and reproducible detection of miRNA with high specificity.

The Agilent Oligo aCGH Prehybridization Buffer is used to wet and condition arrays for hybridization on a Tecan HS 400 Pro or HS 4800 Pro with compatible hybridization chambers. It provides for better distribution of the sample over the active area, and helps prevent the occurrence of gradients in the signals.

The InterPlay TAP Purification Buffer Kit is designed to work with the InterPlay Mammalian TAP System and InterPlay Adenoviral TAP System to recover interacting proteins from mammalian cells. The InterPlay TAP Purification Buffer Kit includes the buffers required to perform tandem affinity purification.

Oligonucleotide GMP manufacturing for human therapeutics

Modifications that enhance the performance of oligonucleotides

Custom adapters for multiplex next-generation sequencing

Predesigned primers for gene expression analysis

Specialized purification to ensure high performance

Larger quantities for in vivo, high throughput and commercial projects  

If you commercialize Molecular Diagnostics (MDx), create Laboratory Developed Tests (LDTs), or conduct preclinical research, then your final kit, assay, or modality must have an extraordinary level of quality to comply with strict regulatory or study standards. In the case of oligonucleotide raw materials available with custom specifications, the only option you should consider is Custom GMP-Grade Oligos.

Modulation of gene expression with modified oligos

TargetSeq® Universal Blocking Oligo series products are used to block self-ligation of adapters to reduce non-specific adapter interaction during probe hybridization and thus to increase data utilization. iGeneTech offers 2 versions of universal blocking oligo for different library input in hybridization workflow, i.e., TargetSeq® Universal Blocking Oligo and TargetSeq® Eco Universal Blocking Oligo for up to 6 μg and 3 μg libr…

Alfa Chemistry provides high-quality oligonucleotide series products including synthesis building blocks and cyclic dinucleotides.

The Odyssey® Infrared EMSA Kit coupled with IRDye® 700 EMSA oligonucleotides is an excellent alternative method to radioisotopic and chemiluminescent detection methods for EMSA analysis and visualization. Using IRDye EMSA reagents, assays can be completed in less than two hours with no gel transfer or film exposure.

A DNA oligonucleotide end-labeled with IRDye 700 infrared dye is a good substrate for protein binding. Using the Odyssey Infrared Imaging System, IRDye infrared dye labeled DNA detection is linear within a 50-fold dilution range from 9.1 fmol to 0.18 fmol.

Creative Biolabs delivers an end-to-end CAR-T development pathway—from target/scFv discovery, CAR design and vectoring, and cell engineering to in-vitro/in-vivo efficacy, IND authoring, and manufacturing support. Modular and GMP-aligned, the platform spans autologous and allogeneic routes (incl. TRAC/Cas9 and mRNA) to de-risk translation for hematologic and solid tumor programs.