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ioGlutamatergic Neurons Huntington's Disease HTT 50CAG/WT Human iPSC-derived glutamatergic neurons

bit.bio

A highly defined, scalable, and consistent source of human central nervous system (CNS) neurons carrying the disease-relevant 50 CAG trinucleotide repeat expansion associated with Huntington’s disease.  ioGlutamatergic Neurons HTT 50CAG/WT have been reprogrammed from human-induced pluripotent stem cells (iPSCs) using bit.bio’s precise reprogramming technology: opti-ox™ (optimized inducible overexpression).

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ioMicroglia Human iPSC-derived microglia

bit.bio

ioMicroglia are human induced pluripotent stem cell (iPSC)-derived microglia, precision reprogrammed using opti-oxâ„¢ technology. Within 10 days post-revival, ioMicroglia are ready for experimentation, expressing (>90%) key markers, including TMEM119, P2RY12, and IBA1. ioMicroglia display key functional traits including phagocytosis and proinflammatory cytokine secretion and can be co-cultured with ioGlutamatergic Neuronsâ„¢.

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