Xevo CDMS

Achieve precise measurement of challenging large and highly heterogeneous molecules that were previously out of reach for mass characterization.

Waters

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Overview:

  • Uncover hidden dimensions in biomolecular analysis across cell and gene therapy, biotherapeutics, biophysical science, and nanoparticle research
  • Investigate protein structure, function, and mechanisms of diseases at scale with measurement of massive, heterogeneous molecules that were previously invisible
  • Achieve real mass clarity with direct, unambiguous, single-ion mass measurement of highly complex, high-mass molecules
  • Gain powerful therapeutic insights with characterization of viral vectors, mRNA, and protein complexes
  • Get intuitive, ready to submit data workflows, and GxP-ready architecture

Specifications:

Technology- Charge detection mass spectrometry with single-ion detection

Detection- Direct mass measurement powered by ELIT technology

Mass Range- 100 MDa and beyond with molecular weight characterization and purity determination of the​ largest, most heterogenous biotherapeutics

Resolution- High-resolution MS analysis of complex mixtures

Sample Types- Ideal for a variety of sample types including viral particles, protein assemblies, and exosomes

Instrument Footprint- Modern benchtop design with revolutionary nanoESI source

User Interface- Intuitive software with guided workflows

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