ioMicroglia Human iPSC-derived microglia
ioMicroglia are human induced pluripotent stem cell (iPSC)-derived microglia, precision reprogrammed using opti-ox™ technology. Within 10 days post-revival, ioMicroglia are ready for experimentation, expressing (>90%) key markers, including TMEM119, P2RY12, and IBA1. ioMicroglia display key functional traits including phagocytosis and proinflammatory cytokine secretion and can be co-cultured with ioGlutamatergic Neurons™.
ioMicroglia are delivered cryopreserved
ioMicroglia display ramified morphology
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bit.bio’s opti-ox powered precision cellular reprogramming converts human pluripotent stem cells into highly defined and functional microglia within days. ioMicroglia provide a consisntet, rapid, functional, and co-culture compatible hiPSC-based model for neurodegenerative disease research and drug development.
Key features:
- Quick: rapidly maturing human microglia that are ready to use within 10 days post-revival.
- Functional: ioMicroglia display key phagocytic and cytokine secretion functions.
- Co-culture compatible: suitable for co-culture studies with neurons.
Applications:
neurodegenerative disease modeling and drug development, neuroinflammation research, co-culture studies, and transcriptome analysis.
