Biomarkers Products & Reviews

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Biomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :

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EVOC® Probes

Owlstone Medical

Exogenous volatile organic compound probes (EVOC Probes) enable targeted, non-invasive assessment of biological pathways. Probes are safe, easy to administer compounds that interact with characterised metabolic pathways with relevance to key disease areas. Using Breath Biopsy, EVOC Probes can be monitored non-invasively on breath, either alone or in parallel with biomarker discovery studies.

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Respiratory VOC Panel

Owlstone Medical

A targeted panel of compounds with established relevance for respiratory diseases enabling high confidence, non-invasive disease detection and monitoring. Each compound is supported by evidence from breath research studies of relevant respiratory diseases and disease processes. The panel is available as an aspect of Breath Biopsy Services and panels for other disease applications are in development.

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In vitro VOC Sampling

Owlstone Medical

Identify prospective biomarkers relevant to key disease processes through in vitro GC-MS analysis. Compatible with headspace sampling from cell cultures, macromolecular preparations and ex vivo samples. Driven by GC-Orbitrap high-resolution mass spectrometry and supported by a rigorous and comprehensive quality assurance process. Results are suitable for comparison with in vivo studies using Breath Biopsy Services.

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Breath Biopsy® Kits

Owlstone Medical

Consumable components of the Breath Biopsy system, required for robust breath sample collection using the ReCIVA Breath Sampler as part of the Breath Biopsy Collection Station. One Kit per sample.

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ReCIVA® Breath Sampler

Owlstone Medical

Reliable and reproducible, non-invasive Breath Biopsy sample collection for high-accuracy analysis of human breath. ReCIVA provides high quality sample collection alongside ease-of-use and patient safety and comfort.  Samples are easy to store and transport and can be analysed using a wide range of techniques. We recommend processing Breath Biopsy samples using high-accuracy GC-MS, available through Breath Biopsy Services.

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Lonestar VOC Analyzer

Owlstone Medical

A versatile and easy to use analyzer for the detection of biomarkers in clinical samples using field asymmetric ion mobility spectrometry (FAIMS). Rapid, portable, sensitive and selective, Lonestar has wide-ranging applications for the detection and quantification of volatile organic compounds (VOCs) from a variety of sample types including feces, urine and breath.

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Bio-Plex Pro Human Serology Reagent Kit

Bio-Rad

Use the Bio-Plex Pro Human Serology Reagent when performing Bio-Plex Pro singleplex or combined (multiplexed) assays with Bio-Plex SARS-CoV-2 N, RBD, S1, and/or S2, and/or nucleocapsid coupled magnetic beads and Human IgA, IgG, or IgM detection in human and non-human primate samples.

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Bio-Plex Pro Human IgG SARS-CoV-2 N/RBD/S1/S2 4-Plex Panel

Bio-Rad

1 x 96-well, includes magnetic capture beads coupled with SARS-CoV-2 nucleocapsid, receptor-binding domain, spike 1, and spike 2 viral proteins, anti-human IgG detection antibody, ready-to-use positive control, ready-to-use negative control, wash buffer, assay buffer, serology sample diluent, detection antibody diluent, streptavidin-PE, 96-well flat-bottom plate, and sealing tape.

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Precision Biology Services

RareCyte, Inc

RareCyte is a full-service provider of Precision Biology™ services utilizing best in class platforms for both spatial biology and liquid biopsy. We deliver quality-focused, end-to-end services from custom assay development to clinical trial testing for researchers, translational scientists, and drug development and diagnostics organizations. Explore Spatial Biology Services and Liquid Biopsy Services. 

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Simoa® Service

RayBiotech Inc.

Single molecule array (Simoa) testing is a protein detection technique that is orders of magnitude more sensitive than standard sandwich based immunoassay techniques. Traditional ELISA measurements are limited to pg/ml levels of detection. The RayBio Ultrasensitive Simoa Testing Services can achieve sensitivity as low as femtogram (fg/ml) levels, allowing the quantification of biomarkers at concentrations previously difficult…

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