Cell-Based Assays Products & Reviews

The iLite® Fc Effector Reporter Gene Bioassays Portfolio offers a variety of reporter gene cell lines and target cells that can be used in MOA-reflective assays to measure the Fc effect of antibodies and other biologics that specifically bind and activate Fc receptors. Using a Luciferase reporter gene system offers a convenient and powerful way of measuring antibodies' in vitro efficacy in triggering ADCC and ADCP.

Svar offers assistance in gene therapy projects through robust platforms suited for all phases of drug development and experience from immunoassasy product development as well as their CRO services. Svar currently offer cell-based assays for Neutralizing antibody assessment and custom-made immunoassays for Total antibody assessment.

Complement biomarker assays target selected biomarkers of high relevance. These assays are important and well-suited for analyses in drug development and academic research. They stand out with very low cross-reactivity and high specificity as they bind neo-epitopes of cleaved products or complexes, where this is relevant.

In diagnosis of Rheumatoid Arthritis (RA), the measurement of anti-CCP is integral. People who test positive for Anti-CCP, are very likely to develop or have already developed RA, but not all who have RA, necessarily develop anti-CCP. Early detection of RA is crucial for reducing tissue damage.

Svar CRO Services provides direct value through an extensive toolbox of in-house products, scientific expertise, and end-to-end customizable solutions – everything to ensure the success of your drug development program.​

The Wieslab® Complement System Classical Pathway kit, available as IVD* and RUO, is a high-precision assay for detecting alternative complement pathway activity in human serum, the RUO is also suitable for primates and porcine samples. It uses ELISA technology with specific detection of C5b-9 for accurate results, offering advantages over traditional assays. *Subject to local registration.

The Wieslab® Complement System MBL Pathway kit, available as IVD* and RUO, is a high-precision assay for detecting alternative complement pathway activity in human serum, the RUO is also suitable for primates and porcine samples. It uses ELISA technology with specific detection of C5b-9 for accurate results, offering advantages over traditional assays. *Subject to local registration.

Wieslab® Complement Screen kit is available as both IVD* and RUO, detects Classical, MBL, and Alternative pathways in human serum samples using ELISA technology with specific detection of C5b-9 for accurate results offering advantages over traditional assays. The RUO is also suitable for primates and porcine samples. It is effective in complement therapeutics evaluation and drug development. *Subject to local registration.

The Factor P Functional assay is an ELISA that combines principles of the functional complement activity assays with the use of labeled antibodies specific for deposited complement proteins. The amount of deposited complement proteins is proportional to the functional activity of Properdin in the sample.

A two-component system of an AAV serotype-producing cell and a iLite®  responsive reporter cell that accurately provides a semi-quantitative NAb assay. The luciferase reporter gene expresses proportionally to the AAV transduction level, enabling precise detection of neutralizing antibodies against AAV. AAV-producing cells are available for serotypes 2, 5, 6, 8, and 9, with customizable options for other serotypes or derivative…

The iLite® CDC bioassay is based on a reporter gene and offers a convenient and powerful way of measuring antibodies' efficacy in eliciting complement-dependent cytotoxicity in test samples, including human serum.

The UNIQO 160 is an all-in-one device for complete automation of indirect immunofluorescence assays (IFA) from primary sample to result proposal. The device performs all assay processing steps, as well as image acquisition and generation of result proposals using the AI-enhanced evaluation software EUROPattern Classifier. Via the EUROLabOffice 4.0 middleware, analyses with the UNIQO 160 integrate seamlessly into lab workflows.

The EUROLabWorkstation ELISA provides fully automated processing of ELISA in laboratories with high sample throughput. The system has a high capacity of up to 15 microplates and can process more than 200 tests per hour. Ten washable needles, complementary accessories and a separate robotic arm for handling the microplates enable unparalleled sample throughput. Intuitive software guides the user through all work steps.

Developing a precise, accurate, and reliable assay is never easy. From raw material sourcing, to technical considerations, to optimization and ultimate scale-up, a development team counters challenges that strain resources and delay timetables. Savvy developers recognize that assay development and optimization move smoother when optimal raw materials and expert support are identified early in the process.

Purified antibodies are indispensable in spatial biology, providing unparalleled detail in cellular and molecular structure characterization. Our high-quality purified antibodies offer exceptional specificity, sensitivity, and reproducibility for diverse applications, from basic research to clinical diagnostics. Moreover, our purified carrier-free antibodies are ready to conjugate (RTC), streamlining your workflow.

PAX-8 (MRQ-50) Mouse Monoclonal Antibody

HiDef Detection™

P504s (13H4) Rabbit Monoclonal Antibody

Cytokeratin 5 & 6 (D5 & 16B4) Mouse Monoclonal Antibody

CD56 (MRQ-42) Rabbit Monoclonal Antibody

DAB Substrate Kit is intended for use in immunohistochemistry (IHC) staining protocols. This reagent is designed to detect target antigens in formalin-fixed, paraffin-embedded tissue sections when used in conjunction with primary antibodies and appropriate secondary antibody conjugates in the IHC staining process. When in the presence of HRP polymer, DAB produces a brown precipitate that can be readily visualized using light m…

GATA3 (L50-823) Mouse Monoclonal Antibody

Cytokeratin Cocktail (AE1 & AE3) Mouse Monoclonal Antibody

Diamond: Antibody Diluent

CD20 (L26) Mouse Monoclonal Antibody