Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Fluent® Laboratory Automation Workstation

Tecan

Tecan has reinvented automation with the Fluent Laboratory Automation Workstation, a unique instrumentation concept built around the application-specific needs of your laboratory. Fluent breaks new ground, delivering more capacity and increased speed. It provides superior precision, throughput and walkaway time, making it easier to get more done, more confidently.

4.5/5.0
|12 Reviews
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Infinite M Plex

Tecan

The Infinite M Plex, a fully-loaded multimode plate reader with monochromator-based optics, offers free wavelength selection and scanning capabilities. Your ready-to-go workhorse for all standard absorbance, fluorescence and luminescence assays. The Infinite M Plex is one of six new tailored reader configurations based on the acclaimed Infinite 200® PRO, designed to simplify your target applications and fit your needs and bud…

4.4/5.0
|8 Reviews
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Infinite F Plex

Tecan

The Infinite F Plex is a fully-loaded multimode plate reader with filter-based optics, offering the highest sensitivity and broadest range of read modes within the Infinite 200 PRO family. Your ideal system for low to medium throughput drug discovery applications, including HTRF® and fluorescence polarization. The Infinite F Plex is one of six new tailored reader configurations based on the acclaimed Infinite 200 PRO, desig…

4.1/5.0
|3 Reviews
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CyBio FeliX

Analytik Jena GmbH+Co. KG

CyBio FeliX – Flexible Benchtop Liquid Handling Flexible pipetting platform for fully automated single to multichannel liquid handling. Discover the new accompanying CyBio FeliX SELECT Head with 8 independent channels and volumes for your hit picking, normalization and pooling applications.

4.5/5.0
|10 Reviews
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CyBio Well Vario

Analytik Jena GmbH+Co. KG

The CyBio Well Vario is CyBio´s automated, simultaneous pipetting platform which can be equipped with 11 interchangeable pipetting heads to offer highest pipetting precision and flexibility in a compact design. A large variety of disposable tips, highly precise ceramic tips or glass capillaries allow liquid transfers in a broad volume range of 4 orders of magnitude (25 nl up to 250 µl) on one pipetting system. 14 differen…

4.3/5.0
|4 Reviews
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Thermo Scientific™ Momentum™ Workflow Scheduling Software

Thermo Fisher Scientific

Achieve new levels of automation performance with the Thermo Scientific™ Momentum™ Workflow Scheduling software-  an industry-leading software platform that enables users to define, execute, and monitor scientific processes and workflows in a powerful yet easy-to-use visual environment. Its intuitive scheduling interface, intelligent data-driven decision-making capabilities, superior connectivity and flexible simulation modes…

4.0/5.0
|2 Reviews
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Millicell® Cell Culture Inserts

Merck

With Millicell inserts, attachment or suspension cells can access media from both their apical and basolateral sides. Cell growth, structure, and function more closely mimic what occurs in vivo. In addition, Millicell inserts make it possible to study both sides of the cell monolayer. Millicell inserts are available for 24-, 12-, or 6-well plates.

4.3/5.0
|1 Review
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CellTox™ Green Cytotoxicity Assay

Promega Corp.

The CellTox™ Green Cytotoxicity Assay measures changes in membrane integrity that occur as a result of cell death. The assay is intended to assess cytotoxicity in cell culture after experimental manipulation. The assay system uses a proprietry asymmetric cyanine dye that is excluded from viable cells but preferentially stains the DNA from dead cells. When the dye binds DNA released from cells, its fluorescence properties are s…

4.3/5.0
|1 Review
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QuantiFluor® dsDNA System

Promega Corp.

The QuantiFluor® dsDNA System contains a fluorescent DNA-binding dye that enables sensitive quantitation of small amounts of double-stranded DNA (dsDNA) in solution.   The quantitation of dsDNA is a very important step in many biological applications, particularly in standard molecular biology techniques. The dye shows minimal binding to single stranded DNA (ssDNA) and RNA, allowing specific quantitation of dsDNA. The…

4.3/5.0
|2 Reviews
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Recombinant RNasin® Ribonuclease Inhibitor

Promega Corp.

Recombinant RNasin® Ribonuclease Inhibitor reliably protects your RNA samples from RNase degradation.   RNases are ubiquitous and degradation can cause significant damage to RNA, hindering downstream reactions. Protect your sample with the most robust inhibitor available-- Recombinant RNasin® Ribonuclease Inhibitor. Recombinant RNasin Ribonuclease Inhibitor Features & Benefits:   Inhibits a broad spectrum o…

4.2/5.0
|3 Reviews
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CellTiter-Glo® 3D Cell Viability Assay

Promega Corp.

The CellTiter-Glo® 3D Cell Viability Assay is a homogeneous method to determine the number of viable cells in 3D cell culture based on quantitation of the ATP present, which is a marker for the presence of metabolically active cells.   This ready-to-use reagent is based on the original CellTiter-Glo® Luminescent Cell Viability Assay chemistry and eliminates the need to combine buffer with lyophilized substrate when prepa…

4.3/5.0
|5 Reviews
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FuGENE ® HD Transfection Reagent

Promega Corp.

FuGENE® HD Transfection Reagent is a novel, nonliposomal formulation designed to transfect DNA into a wide variety of cell lines with high efficiency and low toxicity. The protocol does not require removal of serum or culture medium and does not require washing or changing of medium after introducing the reagent/DNA complex. Additionally, the FuGENE® HD Transfection Reagent has been shown to support transfection in che…

4.3/5.0
|6 Reviews
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NanoBRET™ Target Engagement BET BRD Assays

Promega Corp.

The NanoBRET™ Target Engagement (TE) Intracellular BET BRD Assay measures compound binding at select BET bromodomain target proteins within intact cells. This target engagement assay is based on the NanoBRET™ System, an energy transfer technique designed to measure molecular proximity in living cells

4.3/5.0
|1 Review
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Dual-Luciferase ® Reporter Assay System

Promega Corp.

The Dual-Luciferase® Reporter (DLR™) Assay System(a–f) provides an efficient means of performing two reporter assays. In the DLR™ Assay, the activities of firefly (Photinus pyralis) and Renilla (Renilla reniformis or sea pansy) luciferases are measured sequentially from a single sample. The firefly luciferase reporter is measured first by adding Luciferase Assay Reagent II (LAR II) to generate a luminescent signal lasting at l…

4.4/5.0
|9 Reviews
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Steady-Glo ® Luciferase Assay System

Promega Corp.

High-throughput quantitation of firefly (Photinus pyralis) luciferase expression in mammalian cells is commonly performed by batch processing of 96- and 384-well plates. Steady-Glo® Luciferase Assay System(a,b,c) is designed for this purpose by providing long-lived luminescence when added to cultured cells. The homogeneous assay provides signal half-lives of over 5 hours in commonly used cell culture media without prior sample…

4.5/5.0
|5 Reviews
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CellTiter-Blue® Cell Viability Assay

Promega Corp.

The CellTiter-Blue® Cell Viability Assay provides a homogeneous, fluorescent method for monitoring cell viability. The assay is based on the ability of living cells to convert a redox dye (resazurin) into a fluorescent end product (resorufin). Nonviable cells rapidly lose metabolic capacity and thus do not generate a fluorescent signal. The homogeneous assay procedure involves adding the single reagent directly to cells cultur…

4.3/5.0
|1 Review
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Drug discovery > Target Discovery Products, Equipment and Reviews