Drug discovery > Target Discovery Products & Reviews
Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.
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Ion AmpliSeq HD Panels for Targeted Next-Generation Sequencing
Thermo Fisher ScientificIon AmpliSeq HD technology is a new amplicon-based library preparation technology for Ion Torrent next-generation sequencing (NGS) that gives you the power to design your own panels and find variants with a low limit of detection—down to 0.1% for cell-free DNA samples. This revolutionary technology enables researchers to routinely get answers when ultrahigh sensitivity is required, such as when detecting low-frequency alleles…
NextSeq™ 550Dx Next-Generation Sequencing System
IlluminaThe next level in diagnostic power for the clinical lab
Thermo Scientific™ Q Exactive™ UHMR Hybrid Quadrupole-Orbitrap™ Mass Spectrometer
Thermo Fisher ScientificGo Beyond what you thought possible with Native MS
NEBuilder® HiFi DNA Assembly Cloning Kit
New England Biolabs Inc.NEBuilder® HiFi DNA Assembly Master Mix was developed to improve the efficiency and accuracy of DNA assembly. This method allows for seamless assembly of multiple DNA fragments, regardless of fragment length or end compatibility. This method has been used to assemble either single-stranded oligonucleotides or different sizes of DNA fragments with varied overlaps (15–80 bp). It has utility for the synthetic biology community, a…
Gem21 NeuroPlex™ Serum-Free Supplement
GeminiBioComparable to B27 ® , Gem21 NeuroPlex™ is a chemically defined, serum-free supplement for use in the culture of neural cells and to promote the differentiation of embryonic stem cells into pancreatic and neuronal lines. When used in conjunction with our NeuroPlex ™ serum-free neuronal medium, this product obviates the need for co-culture with astrocyte feeder cells. Supplied as a 50X concentrate.
Alpaqua LE Magnet Plate
alpaquaThe LE Magnet Plate is used with 96-well PCR plates when elution volumes need be kept at a minimum to ensure the highest possible product concentration. This plate allows you to elute in as little as 8-10 µl. The LE Magnet Plate contains a unique plate docking structure and is designed for use with a variety of 96-well PCR plates The LE Magnet Plate is designed for automated* pipetting of 96-well PCR pla…
ThermoGrid™ PCR Plates, 96 well Mini Skirt plate, pkg. of 10
Denville Scientific Inc.Optically Clear for Real Time PCR Raised rim ThermoGrid Plates are rigid, one-piece plates with 0.2ml wells and extremely uniform thin walls for exceptionally rapid temperature transfer from thermal cycler blocks. Each well has a slightly raised rim for compatibility with all types of lid closures and films. The black printed alphanumerics make sample identification easier. All are supplied in natural color and most…
Minutien Pins (0.1mm Rod Diameter)
Fine Science Tools Inc.Fine stainless steel pin for a variety of scientific needs. 500 pins per order. Product specification: 0.0125mm tip diameter. 0.1mm rod diameter.
Quick Ligation™ Kit
New England Biolabs Inc.The Quick Ligation™ Kit enables ligation of cohesive end or blunt end DNA fragments in 5 minutes at room temperature. (25°C ) Fast - 5 minutes for cohesive or blunt ends. Convenient - ligation performed at room temperature. Flexible - suitable for all common ligation reactions.
respons®910
DiaSysrespons®910 is a compact and fully-automated bench top analyzer for maximum efficiency. During its development, special attention was paid to easy handling and optimized work flow thus leading to the ideal clinical chemistry system for many laboratories. The new software version 4.8.0.8 is available for respons®910 devices. DiaSys highly recommends to up-grade all installed respons®910 analyzers because it eases daily labor…
Amnis® Imaging Flow Cytometers
MerckCombining microscopy and flow cytometry, Amnis imaging flow cytometry systems provide bright-field, dark-field (SSC), and several fluorescent images of each cell in flow, at high speed. Paired with IDEAS® software for quantitative image analysis and population statistics, the technology gives you the ability to address complex biology that traditional flow cytometers can't resolve. Not only do the instruments reveal spatial lo…
Live/Dead Cell Viability Assay Kit (for Mammalian Cells)
BioVision IncThis assay kit provides an easy-to-use, non-radioactive, histological and FACS-based method for measuring cell proliferation, cell viability, chemotaxis, cytotoxicity and apoptosis. The kit provides a two-color fluorescence method that is based on the simultaneous determination of live and dead cells using two different dyes. Live cells and intracellular esterase hydrolyzes the dye to produce a hydrophilic, strongly fluore…
Costar 3596 96-well cell culture plates with lid, flat well, treated, sterile, 50/cs
Cole-Parmer Instrument Co.Optically clear, virgin polystyrene is treated for optimal cell attachment Stacking beads and uniform footprints (86 x 128 mm) facilitate stacking and handling Serrations on plate flange/skirt enable you to easily distinguish plates from lids when handling stacks of clusters Lids feature individual condensation rings to reduce well-to-well contamination Gamma radiation sterilized and certified pyrogen-free
BD LSRFORTESSA
BD BiosciencesThe BD LSRFortessa™ cell analyzer offers the ultimate in choice for flow cytometry, providing power, performance, and consistency. Designed to be affordable and expandable, the BD LSRFortessa has the flexibility to support the expanding needs of multicolor flow cytometry assays.
NovaSeq 6000 Sequencing System
IlluminaScalable throughput and flexibility for virtually any sequencing method, genome, and scale of project.
CloneR™
STEMCELL Technologies Inc.Defined supplement for single-cell cloning of human ES and iPS cells
TrypLE Reagents
Thermo Fisher ScientificGibco TrypLE reagents are highly purified, recombinant cell-dissociation enzymes that replace porcine trypsin. These reagents are ideal for dissociating attachment-dependent cell lines in both serum-containing and serum-free conditions, and can be directly substituted for trypsin without protocol changes.
OptiPrep™
PROGENOptiPrep™ is a ready-made, sterile and endotoxin-tested solution of iodixanol. Suitable for the isolation of many different cell types from blood and tissue (e.g. monocytes, lymphocytes, granulocytes, platelets, dendritic cells, megakaryotic progenitor cells; liver non-parenchymal cells, islet of Langerhans cells, spermatozoa; plant protoplasts) as well as for the isolation of cell organelles (e.g. nuclei, mitochondria, peroxi…