Thermo Scientific™ 253 Plus 10 kV Isotope Ratio MS
Utilize the new gold standard in IRMS. The new Thermo Scientific™ 253 Plus™ yet again redefines high performance for isotope ratio mass spectrometry.
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IRMS users with low sample volumes and requiring higher sensitivity should buy.
Gas CO2, H and O2 analysis
Most sensitive and powerful instrument in the field available. No competition in the market due its magnet power and sensitivity. Lowers the minimum initial sample size by up to 10 times.
Review Date: 5 Dec 2019 | Thermo Fisher Scientific
High throughput easy to use top class instrument.
Dope testing and analysis of origin.
High sensitivity and repeatability of the equipment due to its 10 KV magnet. Leaves all the competitors behind.
Review Date: 26 Jun 2019 | Thermo Fisher Scientific
Utilize the new gold standard in IRMS. The new Thermo Scientific™ 253 Plus™ 10 kV IRMS yet again redefines high performance for isotope ratio mass spectrometry. It builds on the robustness, linearity, and sensitivity only available in the Thermo Scientific 10 kV IRMS technology. Technical innovations for the 253 Plus 10 kV IRMS improve sample utilization, stability, background and signal-to-noise resulting in ultimate precision on smallest sample sizes.
Proven Thermo Scientific 10 kV IRMS technology
- “Extra bright” 10 kV EI ion source enables highest sensitivity and linearity in IRMS
- All-metal sealed ion source and analyzer with gold gaskets
- The only IRMS with variable conductance (VISC)
- Analytical dynamic range greater than 107
- Hydrogen continuous flow capability
- Fully integrated workflow solutions in Thermo Scientific™ Qtegra™ ISDS software suite
GC-MS-IRMS: Undisputable results by coupling of GC-IRMS with high-resolution mass spectrometry for final confirmation in sports drug testing
Gas chromatography coupled with isotope ratio mass spectrometry is routinely applied in doping controls. It allows distinguishing between endogenous steroids from their synthetic analogs in urine by the determination of ¹³C/¹²C isotope ratios.
In this application note, see how combining the Thermo Scientific Delta V or the Thermo Scientific 253 Plus IRMS system with Thermo Scientific Q Exactive GC connected to a single Thermo Scientific Trace 1310 GC gas chromatograph provides a refined methodology for doping control. Plus, it will explore how simultaneous analysis by an HRAM GC/MS system enables confirming the peak identity and purity with high accuracy and confidence.
