Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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The PhysioMimix™ OOC Range of Single and Multi-organ Microphysiological Systems (MPS) by CN Bio

CN Bio

PhysioMimix™ microphysiological systems generate in vitro microtissues that mimic the structure and function of human tissues and organs. Through the simulation of human biological conditions, they bridge the gap between traditional cell culture and human studies, reliably predicting drug effects to facilitate the accelerated development of safe and efficacious therapeutics. 

4.9/5.0
|3 Reviews
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BIOFLOAT™ Spheroid Culture

SARSTEDT AG

The new BIOFLOAT™ cell culture surface for spheroid culture features a high-grade anti-adhesive property. This makes it possible for the cultivated cells to form primarily cell-cell contacts without adhering to the surface of the vessel. BIOFLOAT™ thus makes it possible for you to produce perfect spheroids quickly and reproducibly. 

4.7/5.0
|5 Reviews
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THEANT

Malvern Panalytical

A new paradigm in weighing advances the fusion process: TheAnt serves to automatically weigh the sample and dispense the flux with extreme precision, to an accuracy of one tenth of a milligram. Specially designed for: Laboratories with high sample throughput for analysis by XRF, AA and ICP Perfect manipulation with Claisse borate fluxes Distinguishing features: Automatic weighing of sample Automatic dispensing of…

5.0/5.0
|1 Review
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M4 FLUXER

Malvern Panalytical

Prepares : Glass disks for XRF analysis Solutions for AA and ICP analysis Processes : Cement, ceramic, slag, glass, silica, carbonates Mining and geological samples Sulfides Bauxites, fluorides Polymers, catalysts Pure metals, ferroalloys and other alloys Samples containing highly volatile elements Distinguishing features : Precise control of low and high fusion temperatures NO calibration, NO c…

5.0/5.0
|1 Review
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Millicell® 24 & 96-well Cell Culture Insert Plates

Merck

Millicell® cell culture insert plates are a patented device designed to support cell growth and differentiation of endothelial and epithelial cell lines, including CaCo-2. The Millicell® device is available with a 0.4 µm PCF and a variety of PET membrane pore sizes. The plate is designed for maximum user convenience and incorporates features such as apical assist for easier pipetting and basolateral access.

5.0/5.0
|1 Review




Multi-Gen 7XL Homogenizer Package

PRO Scientific, Inc.

Multiple sample homogenizing can be time consuming and can create concerns of cross-contamination. PRO Multi-Sample Homogenizer Kit provides the most effective method for homogenizing multiple samples at a time within 1.5ml - 50ml tubes as well as it can eliminate cross-contamination concerns.

4.7/5.0
|9 Reviews



DPPIV-Glo™ Protease Assay

Promega Corp.

The DPPIV-Glo™ Protease Assay is a homogeneous, luminescent assay that measures dipeptidyl peptidase IV (DPPIV) activity. DPPIV is a serine protease that cleaves N-terminal dipeptides from polypeptides with L-proline or L-alanine at the penultimate position. The DPPIV-Glo™ Assay provides a proluminescent DPPIV substrate, Gly-Pro-aminoluciferin, in a buffer system optimized for DPPIV and luciferase activities. The addition of a…

4.7/5.0
|1 Review
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ONE-Glo™ Luciferase Assay System

Promega Corp.

The ONE-Glo™ Luciferase Assay System provides a highly sensitive, robust, homogeneous assay for detection of firefly luciferase reporter gene expression in mammalian cells. Ideally suited for high- and ultrahigh-throughput applications, the ONE-Glo™ Assay contains a new luciferase substrate, resulting in a reagent that is more stable, more tolerant to sample components, and has less odor than standard luciferase assay reagents…

4.8/5.0
|4 Reviews
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ApoTox-Glo™ Triplex Assay

Promega Corp.

The ApoTox-Glo™ Triplex Assay combines three assay chemistries to easily assess viability, cytotoxicity and apoptosis events in the same cell-based assay well. First, viability and cytotoxicity are determined by measuring two differential protease biomarkers simultaneously with the addition of a single nonlytic reagent containing two peptide substrates. The live-cell protease activity is restricted to intact viable cells and i…

4.6/5.0
|3 Reviews
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Griess Reagent System

Promega Corp.

The Griess Reagent System measures nitrite (NO2–), which is one of two primary stable and nonvolatile breakdown products of nitric oxide (NO). Nitric oxide is an important physiological messenger and effector molecule in many biological systems, including immunological, neuronal and cardiovascular tissues. This assay relies on a diazotization reaction that was originally described by Griess in 1879. Through the years, many mod…

4.7/5.0
|1 Review
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QuantiFluor™ RNA System

Promega Corp.

The QuantiFluor™ RNA System contains a fluorescent RNA-binding dye that enables sensitive quantitation of small amounts of RNA in solution. Detecting and quantitating small amounts of RNA is a very important step used in many biological applications, particularly in molecular biology techniques. These include measuring yields of in vitro transcribed RNA and measuring RNA concentrations before performing Northern blot anal…

4.7/5.0
|5 Reviews
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ROS-Glo™ H2O2 Assay

Promega Corp.

The ROS-Glo™ H2O2 Assay is a homogeneous, fast and sensitive bioluminescent assay that measures the level of hydrogen peroxide (H2O2), a reactive oxygen species (ROS), directly in cell culture or in defined enzyme reactions.   This assay allows identification of conditions or test compounds, such as small molecule inhibitors or inducers, that alter ROS levels. The scalable multiwell format couples a stable luminescent si…

5.0/5.0
|2 Reviews
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Trypsin/Lys-C Mix, Mass Spec Grade

Promega Corp.

Trypsin/Lys-C Mix, Mass Spec Grade, is a mixture of Trypsin Gold, Mass Spectrometry Grade, and rLys-C, Mass Spec Grade. The Trypsin/Lys-C Mix is designed to improve digestion of proteins or protein mixtures in solution.   Using the conventional trypsin digestion protocol (i.e., overnight incubation at nondenaturing conditions), Trypsin/Lys-C Mix improves protein digestion by eliminating the majority of missed cleavages,…

5.0/5.0
|2 Reviews
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