Drug discovery > Target Discovery Products & Reviews

A Fluorometric Method for Estimating the Number of Nonviable Cells Present in Multiwell Plates

Measure Kinase-Ligand Affinity in Live Cells The NanoBRET™ Target Engagement (TE) Intracellular Kinase Assay measures compound binding at select target kinases in intact cells. The assay is based on the NanoBRET™ System, an energy transfer technique designed to measure molecular proximity in living cells. The NanoBRET™ TE Assay measures the apparent affinity of test compounds by competitive displacement of the NanoBRET™ tra…

Simple, Plate-Based Assay for Real-Time Apoptosis Detection

Superior Size Selection and Recovery for NGS and PCR

A Simple, Non-Radioactive Assay to Measure Glucose Uptake Inside Cells

Capped or Uncapped RNA Transcripts for in vitro or in vivo Translation

Digitonin can be used in cell viability and cytotoxicity assays. It is a detergent solution useful for permeabilizing cells and for creating a cytotoxicity chemistry positive control. Supplied at 20mg/ml in DMSO

The Caspase-Glo ® 3/7 Assay System is  a highly sensitive caspase activity assay for use in plate-reader assays.

MOA-based functional bioassay to measure Fc effector activity.

A best-in-class DNA transfection reagent for your research.

Stable at Room Temperature and Easy to Use

The CellTiter 96® AQueous One Solution Cell Proliferation Assay is a colorimetric method for determining the number of viable cells in proliferation, cytotoxicity or chemosensitivity assays. The CellTiter 96® AQueous One Solution Reagent contains a tetrazolium compound [3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium, inner salt; MTS(a)] and an electron coupling reagent (phenazine ethos…

The pGEM®-T Easy Vector Systems are convienent systems to clone PCR products.   They offer all of the advantages of the pGEM®-T Vector Systems with added convieneice of recognition sites for EcoRI and NotI flankin the insertion site. Thus, several options exist to remove the desired insert DNA with a single restriction digestion. The pGEM(R)-T Easy Vectr System II contains JM109 Competent Cells in addition to all pf the…

The GSH-Glo™ Glutathione Assay is a luminescence-based assay for the detection and quantification of glutathione (GSH). The assay is based on the conversion of a luciferin derivative into luciferin in the presence of glutathione, catalyzed by glutathione S-transferase (GST). The signal generated in a coupled reaction with firefly luciferase is proportional to the amount of glutathione present in the sample. Luminescence is gen…

Broad portfolio of products for knockdown of gene expression

The world’s only laser-based microplate nephelometer

Most flexible Multi-mode Microplate Reader for Assay Development

Live-cell analysis system

Fast, accurate, and automated brightfield and fluorescent cell counting

Lux3 BR is a small brightfield live-cell imager, equipped with a high-quality 6.4 MP CMOS camera. It is designed to work inside a standard cell culture incubator without disturbing temperature, airflow, and optimum culture conditions. Detailed brightfield images can be captured using the new device. In both x- and y-direction, 2072 pixels combined with 1.45 mm field of view provide a resolution of 0.7 µm/pixel. 

High-throughput live-cell analysis system

The VANTAstar Multi-Mode Microplate Reader is a compact multi-mode microplate reader compatible with all plate formats up to 384 wells.

The Omni FL is a fluorescence (green and red) and brightfield microscope designed to image live cells directly inside a cell culture incubator. The device can be used for continuous cell culture monitoring, as well as endpoint assays. Applications: cell viability, transfection efficiency, co-culture analysis, and more.

The FLUOstar Omega is a multimode microplate reader perfect for life science research laboratories.

LUMIstar Omega - Flexible Luminometer for Measuring Flash and Glow Luminescence