Drug discovery > Basic Research Products & Reviews

The BX3 Series of upright microscopes provides the convenience, comfort and configurability needed to help make your work more efficient. 

Features include... Rapid vessel exchange with quick-release vessel clamp and hose couplings. Range of single and double jacketed vessels from 100ml to 5 litres. New range of process vessels to mimic larger scale plant or manufacturing reactors. Accepts all leading brands of overhead stirrer and allows easy, tool free adjustment. Triple support stand features heavy duty stainless steel support rods for strength and…

The Model P-97 micropipette puller is the latest generation of the Flaming/Brown type puller for fabrication of micropipettes, patch pipettes and microinjection needles. While retaining many of the features on the Model P-87, the P-97 offers improvements in mechanical, electronic and software design. The result is better control of the pulling process and a higher degree of reproducibility. Features: Environmental chamber…

The GSH-Glo™ Glutathione Assay is a luminescence-based assay for the detection and quantification of glutathione (GSH). The assay is based on the conversion of a luciferin derivative into luciferin in the presence of glutathione, catalyzed by glutathione S-transferase (GST). The signal generated in a coupled reaction with firefly luciferase is proportional to the amount of glutathione present in the sample. Luminescence is gen…

Primarily directed against mature 17kDa human IL-1beta. In ELISA formats and other immunoreactive assays, the antibody will recognize 10% of the non-denatured (native) 31kDa IL-1beta precursor containing samples, but will detect all of the 17kDa mature molecule. Also detects primate IL-1beta in the same formats using similar dilutions.

The Zyppy™ Plasmid Miniprep Kit is the fastest and simplest method available to efficiently separate plasmid DNA from E. coli.

Application Adjuvanticity Assay: EIA titer for test mice is at least 2X greater that that of control mice. Biochem/physiol: Actions Sigma Adjuvant System is for use in mice. It is a stable oil-in-water emulsion that may be used as an alternative to the classical Freund′s water-in-oil emulsions. This adjuvant is derived from bacterial and mycobacterial cell wall components that provide potent stimulus to the immune system. Phys…

FastDigest® restriction enzymes are an advanced line of restriction enzymes for rapid DNA digestion. All FastDigest® enzymes are 100% active in the universal FastDigest® Green buffer and are able to digest DNA in 5-15 min. This enables any combination of restriction enzymes to mork simultaneously in one reaction tube and eliminates the need for sequential digestions. FastDigest® enzymes can be used to digest plasmid, genomica…

From BlueSens GmbH, the BCP-CO2 is a reliable sensor for the laboratory and the industrial use. You can choose between a robust version with an aluminum housing or a compact version with a PA-plastics housing. Whatever you decide for – BCP-CO2 optimizes bioprocessing easily, efficiently and precisely. The field of application is large – whether in the bioreactor or in the fermenter, in the laboratory or on the industrial large…

Streamline your infrared microanalysis workflow with the Thermo Scientific™ Nicolet™ iN™10 Infrared Microscope.

INTERFERin™-HTS is a new generation siRNA transfection reagent especially developed for high throughput screening (HTS) applications providing great silencing efficiency, excellent reproducibility and high cell viability with very low amounts of reagent. INTERFERin™-HTS is cost-effective, easy to handle, compatible with serum and antibiotics, and comes with reverse and forward protocols for 96- and 384-well plates. Great s…

Bioneer’s AccuPrep® Genomic DNA Extraction Kit allows the extraction of total genomic DNA from whole blood, lymphocytes, mammalian tissue and cultured cells. Average yield of 6 μg of total genomic DNA from 200 μl of whole human blood and up to 20 μg from 5 x 106 lymphocytes, 25 - 50 mg mammalian tissue, or 104 -108 cultured cells.AccuPrep Genomic DNA Extraction Kit employs glass fibers, fixed in the AccuPrep column, that speci…

Blood RNA PrepMate™ is designed for rapid isolation of high-purity total RNA from Blood or cultured cells based on the guanidinium salt-lysis method. The extracted total RNA from PrepMate can be used for Northern analysis, dot blot hybridization, poly-A (+) selection, RNase protection assays, and molecular cloning, or RT-PCR. PrepMate is an economical RNA kit that provides excellent yields of pure total RNA.

Bioneer’s HotStart DNA polymerase uses an exclusive enzyme-mediated Hot Start PCR method that, unlike most other HotStart PCR chemistries, completely releases all polymerase activity during the first denaturation step. Top DNA polymerase is completely inhibited by pyrophosphate at temperatures below 70°C. However, at temperatures above 70°C, a thermostable pyrophosphatase initiates pyrophosphate hydrolysis and activates the DN…

Brilliance™ MRSA is a new and improved chromogenic screening plate for MRSA. The medium combines excellent sensitivity with the simplicity of a chromogenic plate to create an invaluable tool in the implementation of infection control policy. Technique Brilliance MRSA Agar can be inoculated from screening swabs taken from hospital patients or staff, an isolated colony or from liquid suspension, according to local guidelines. T…

The PatchStar is an ultra-stable, super smooth micromanipulator with extremely low electrical noise. With a versatile, modular design and user friendly responsive controls, the PatchStar is perfect for a wide range of electrophysiological, microinjection and other demanding positioning requirements. Ergonomically designed in collaboration with leading electrophysiologists, the PatchStar will increase productivity and ensure qu…

SliceScope Pro systems are a range of fully integrated and motorised patch clamping solutions. They allow the user to control manipulators, microscope platforms, microscope condenser and objective focus all from simple user consoles. The SliceScope a fixed stage, focussing nosepiece microscope. This defines a new bench mark in imaging and electrophysiology research. Developed in collaboration with the world leading researchers…

Eliminate electrical interference from any analog signal, without filtering. Ideal for electrophysiology applications like EKG, EMG, and EEGs. Removes 50/60hz noise and harmonics caused by grounding problems, high gain amps, audio equipment, etc.

12VDC solenoid valve controller for real-time or pre-programmed liquid switching in perfusion, physiology, biophysics, electrochemistry, or general liquid-handling research applicationsIncrease reproducibility with 1 millisecond accuracyValveGuard™ technology detects bad valvesPrevent damage to your ValveLink and easily observe problem valves.Run experiments automatically - even unattendedMicroprocessor-based for accuracy and…

Computer-controlled microelectrode amplifier with a high-speed current clamp capable of sharp-electrode, field potential or ion-selective measurements, and a patch clamp for whole-cell, excised or cell-attached patches, bilayers, and electrochemistry with voltammetry or amperometry. MultiClamp 700B is shipped with the following,MultiClamp 700B Amplifiero Two 1-CV-7B headstageso US power cord (Part Number 1-3010-0011)o Europea…

The Marianas™ research microscopy imaging system combines state-of-the-art optics, custom electronics, detectors, and computers for both live and fixed cell applications. 3i’s SlideBook™ software takes full advantage of the system's automation by seamlessly integrating components, including x-,y- and z-stage motion, filter control and light shuttering. Methods: • 7D imaging • FRET • TIRF • FLIM • Ratiometric imaging • Photoman…

Fernbach design increases surface area for gas exchange Made from optically-clear polycarbonate Ideal for shaker culture applications Baffled bottoms improve mixing and increase gas exchange Vent caps supplied in every case of product for applications requiring sterile gas exchange Sterilized by gamma radiation and nonpyrogenic RNase- and DNase-free

Genomic research techniques are rapidly advancing, so the quality of your oligonucleotides used in research is paramount. Thermo was the first company to purify all synthesised oligonucleotides by reverse-phase HPLC as standard, at no extra cost, guaranteeing consistently high product quality and reproducibility of experimental results. We are experts at synthesising oligonucleotides and have built up years of synthesis knowle…

Pkg of 1, 4–15% precast polyacrylamide gel, 12+2-well, 45 µl, for use with Criterion and Criterion™ Dodeca™ cells

Vertical midi-format electrophoresis cell, includes buffer tank, lid with power cables, 3 sample loading guides (12+2-well, 18-well, and 26-well)