Drug discovery > Basic Research Products & Reviews

Cellstain-Double Staining Kit is utilised for simultaneous fluorescence staining of viable and dead cells.  Flurometric microscope detection, simultaneous determination of viable and dead cells.

With in excess of 150,000 installed units worldwide, Mantis has become the low magnification stereo viewer of choice in a vast range of laboratory and industrial applications. All of these applications require bright, well contrasted images that are easy to view, especially for prolonged periods. The patented spatial imaging technology used by Mantis provides true optical 3D images, together with large working distances an…

Extremely accurate refractometer for gases and anaesthetic gas mixtures

The DX41 offers excellent optical performance with a stable compact design and reduced footprint providing ample bench space for accessories. Vision Biomed’s infinity corrected optics provide outstanding contrast and resolution. As a system microscope, Vision Biomed’s DX41 is particularly well suited to clinical and research microscopy applications.  A modular design adds to its versatility with optimised ergonomics making f…

The DX61 offers life science professionals convenience, performance and flexibility combining infinity corrected optics with innovative mechanical design and is particularly suited to most tissue culture applications. - Outstanding optical performance - Infinity optical system- Ergonomically optimised and compact design- Optional ISIS Expanded-Pupil eyepieces increase eye-reliefVision Biomed have developed the DX61 with the…

The DX21 raises the bar in educational and clinical examination. The infinity optical system provides clear sharp images and Vision Biomed ’s ergonomic design ensures comfortable viewing over extended periods of use.- Superb ergonomics for optimum operator comfort- Outstanding optical performance - Modular design allows for easy addition of accessories - Compact stable design The DX21 is a robust, simple to use, purpose built…

Isis expanded pupil is newly patented multi-lenticular technology to a new device designed to enhance the ergonomics of all conventional binocular microscopes. Vision’s Isis accessory fits directly into the microscope’s eyepiece tubes to deliver Expanded Pupil technology, offering an exit ray bundle twelve times larger than a traditional eyepiece.Expanded Pupil technology allows a much greater freedom of operator head movement…

GeneJuice® Transfection Reagent is a proprietary formulation optimized for maximal transfection efficiency, ease of use, and minimal cytotoxicity. This transfection reagent is a superior alternative to a wide variety of other techniques including calcium phosphate coprecipitation, electroporation, microinjection, biolistic particle delivery, and complex formation with DEAE-dextran. Whereas many available transfection reagents…

Pellet Paint® NF Co-Precipitant* is a non-fluorescent dye-labeled carrier compatible with fluorescent sequencing. It facilitates rapid removal of BigDye™ Terminators (PE Corp.) during the alcohol precipitation of cycle sequencing reaction products. Cycle sequencing reactions can be precipitated rapidly with centrifugation times of 10 minutes. The easily visualized carrier provides a simple confirmation that precipitation has o…

Rapid, quantitative precipitation of DNA and RNA, including PCR clean-upPellet Paint® Co-Precipitant* is a visible dye-labeled carrier formulated specifically for use in alcohol precipitation of nucleic acids (1, 2). The two minute precipitation requires no low temperature incubations or prolonged centrifugation. Both RNA and DNA are efficiently precipitated from even the most dilute solutions (2 ng/ml) and the pellet is easil…

Overnight Express™ Instant TB Medium is a complete granulated culture medium for high-level protein production without the need to monitor cell growth in the pET and other IPTG-inducible bacterial expression systems. Cell mass and target protein yield are often increased several-fold as compared with induction using IPTG. The method is based on media components that are metabolized differentially to promote growth to high dens…

White solid. Aminoglycoside related to gentamycin that inhibits prokaryotic and eukaryotic protein synthesis. Toxic to bacteria, yeast, protozoans, helminths, higher plant, and mammalian cells. Widely used in the selection of eukaryotic expression vectors carrying the bacterial neor/kanr genes. The product of these genes, aminoglycoside 3¡ä-phosphotransferase, inactivates G418, neomycin, and kanamycin by phosphorylation. Intro…

Light brown lyophilized solid. Working concentration 50 mg/ml - 1 mg/ml for mammalian cell selection. Unique aminoglycoside antibiotic that inhibits the growth of prokaryotic (bacteria) and eukaryotic microorganisms (yeasts) and mammalian cells. Inhibits protein synthesis at the translocation step on the 70S ribosome and causes misreading of the mRNA. Hph, a gene from E. coli, encodes resistance to hygromycin B and can be isol…

The ProteoPlex™ 16-Well Murine Cytokine Array Kit is designed for multiplex detection and measurement of 10 important mouse cytokines in parallel from up to 15 experimental samples. The 10 analytes measured in the kit are pro- and anti- inflammatory cytokines important for the study of immune system regulation and diseases such as asthma and arthritis. Each well on the slide contains a microarray of spotted antibodies with fou…

Novel protein markers for visible tracking & accurate sizing on any Western blotTrail Mix™ Western Markers consist of the Perfect Protein™ Western Markers supplemented with a group of three prestained indicator proteins to allow direct visualization of protein mobility during electrophoresis. Trail Mix Western Markers and Western Blot Kits have all of the features of Perfect Protein Western Markers and Western Blot Kits, plus…

The His•Tag® Monoclonal Antibody is a mouse monoclonal antibody (IgG1) directed against the His•Tag sequence encoded by many of Novagen's expression vectors as well as many other commercially available vectors. The antibody recognizes five consecutive histidine residues regardless of the surrounding amino acid context. The high affinity (Kd = 5 × 10 to 8–1 × 10–9 M) enables sensitive, specific detection of His•Tag fusion prote…

Benzonase Nuclease - Effective viscosity reduction and removal of nucleic acids from protein solutions Benzonase Nuclease is a genetically engineered endonuclease from Serratia marcescens. It degrades all forms of DNA and RNA (single stranded, double stranded, linear and circular) while having no proteolytic activity. Benzonase Nuclease is effective over a wide range of conditions and possesses an exceptionally high specif…

The most common method for transformation of plasmids into E. coli is to use chemically competent cells. Although competent cells can be prepared in the laboratory, greater efficiency, reproducibility and convenience are achieved using prepared competent cells. Novagen offers the widest selection of competent cells available for protein expression. Our strains offer a variety of options that enable you to maximize the yield an…

Novabiochem® building blocks for routine peptide synthesis applications

Pseudoproline dipeptides are undoubtedly the most powerful tools described to date for enhancing synthetic efficiency in Fmoc SPPS. Novabiochem® now offers 28 pseudoproline dipeptides - representing the widest selection on the market today The routine use of pseudoproline dipeptides has been found to: Avoid costly and unnecessary repeat syntheses of failed sequences Increase purity of crude products Simplify HPLC puri…

Calbiochem® supplies a wide variety of products for the study of apoptosis, includingActivators and Inhibitors Antibodies and Blocking Peptides Assay Kits Caspase-related products Mitochondrial Permeability-Transition Reagents and Related Products Poly(ADP-Ribose) Glycohydrolase (PARG) Inhibitors Poly(ADP-Ribose) Polymerase (PARP) Inhibitors Telomerase Products View the online interactive pathways to easily locate the product…

The pET System is the most powerful system yet developed for the cloning and expression of recombinant proteins in E. coli. Based on the T7 promoter-driven system, Novagen’s pET System has been used to express thousands of different proteins. pET Vectors are supplied as purified plasmid DNA (10 µg) plus an Induction Control strain (supplied as a glycerol stock). Complete sequences and detailed vector maps are available.

The D-Tube™ Dialyzers can be used for dialysis and electroelution of proteins or nucleic acids from polyacrylamide or agarose gels. The disposable, single-use tubes require no syringes, microcentrifuges, or laborious steps to manipulate small samples volumes. The sample is added and removed using a standard laboratory pipette. Available with molecular weight cut-offs from 3.5 to 14 kDa, the D-Tube Dialyzers are designed in thr…

May be used in a variety of laboratory assays Flat bottom strips are designed to easily break apart and may be used in an style strip holder that allows each individual well to be positioned back into the plate once broken High binding surface binds medium (>10kD) and large biomolecules that possess ionic groups and/or hydrophobic regions. Binding capacity is approximately 400 to 500ng IgG/cm2. Ideal for immunoassays Reco…