Drug discovery > Basic Research Products & Reviews

Agilent Seahorse XF Hu T Cell Activation Assay Kit measures human (Hu) T cell activation response within several minutes of stimulation using Seahorse XF Analyzers. This is accomplished via measuring proton efflux rates (PER) associated with glycolytic pathway-dependent energy production, and is built on the principle that T cell activation is accompanied by a rapid switch in cellular energy production and intermediate demand…

The Agilent Seahorse XF Palmitate Oxidation Stress Test Kit provides validated reagents to measure long chain fatty acid oxidation (FAO) via assessing changes in oxygen consumption (OCR) in intact cells. The kit includes the XF Palmitate-BSA FAO Substrate, L-carnitine, etomoxir, as well as oligomycin, FCCP, and rotenone/antimycin A to determine the intrinsic rate and capacity of a cell to oxidize palmitate in the absence or l…

Agilent offers a new microplate product line to support cell culture and imaging. These high-quality polystyrene products provide superb optical clarity and comply with ANSI standards for compatibility with automated processing systems. TC surface treatment enhances cell attachment while the included lid maintains a sterile growth environment with low risk of cross-contamination. The product designs feature easy stacking, alp…

SureSelect Cancer CGP assay offers comprehensive genomic profiling for solid tumors. This pan-cancer NGS panel enables detection of somatic variants, including single nucleotide variants (SNVs), copy number variants (CNVs), insertions/deletions (indels), translocations (TLs), gene fusions, and the immuno-oncology biomarkers TMB (tumor mutational burden) and MSI (microsatellite instability).

The Cary 3500 Compact UV-Vis is a double beam spectrophotometer featuring new and unique measurement capabilities that can be deployed in regulated environments. The system performs ambient and temperature-controlled experiments with air-cooled Peltier temperature control, and it accurately analyzes low volume samples—providing in-depth analysis by collecting up to 250 data points per second. The xenon flash lamp—complete with…

Integration of the xCELLigence Real Time Cell Analyzer (RTCA) HT instrument with the BioTek BioSpa 8 automated incubator expands the screening throughput of your RTCA HT instrument to eight 384-well plates. Label-free high-throughput xCELLigence Real-Time Cell Analysis is ideal for screening viral mediated cytopathic effects (CPE), neutralizing antibodies, antibody-dependent cytotoxicity (ADCC), and compound mediated cytotoxi…

Designed for smaller studies, the SureSelect DNA Capture Arrays complement Agilent's in-solution SureSelect Target Enrichment System, which is designed for medium to large-scale NGS studies of tens through thousands of samples, including automated high-throughput workflows.

Agilent’s market leading SureSelect platform provides a complete portfolio of catalog and custom products, providing the flexibility you need from discovery to follow-up studies. Agilent’s custom solutions offer the only available method for target enrichment of RNA, allowing you to target your regions of interest using our free web portal SureDesign. Custom solutions are available for DNA and RNA target enrichment. • The only…

eArray is a web-based application that enables you to harness the flexibility of Agilents SurePrint oligo manufacturing technology in the creation of custom microarray designs and oligo libraries.  eArray, free to all registered users, allows you to create assays that are specific to your research needs. Create custom microarray designs for Gene Expression, microRNA, Model Organisms, CGH, ChiP-on-chip, and DNA Methylation.Crea…

The Agilent SurePrint G3 Human GE 8x60K Microarrays offer the same high sensitivity and accuracy provided by the earlier generation arrays but adds the benefits of extended coverage, greater throughput, and increased cost savings. The new SurePrint G3 Human GE 8x60K Microarrays and Human GE 4x44K v2 Microarrays are based on updated transcriptome databases for mRNA targets, while the SurePrint G3 arrays also include probes for…

Compatible with 96-well plates from any manufacturer, the Resprep VM-96 is designed for performance and accuracy.

For Sciex Turbo V Sources

Unique service that enables you to expand your own organoid lines to a scale large enough to suit your individual requirements. Generate more than six million assay-ready, reproducible organoid models to support your compound screening, cell model creation, or other applications. 

The CellXpress.ai™ Automated Cell Culture System is an AI-driven cell culture innovation hub that gives your team total control over demanding cell culture feeding and passaging schedules—eliminating time in the lab while maintaining a 24/7 schedule for growing and scaling multiple stem cell lines, spheroids, or organoids.

Make your innovations a reality with the first unified, cloud-native SaaS R&D solution that streamlines scientific complexity and promotes collaboration.

Consistent, Traceable Sample Card Processing. The easyPunch STARlet provides everything needed for hands-free sample card punching and extraction, along with sample traceability.

The CGX10 Cell Isolation System is a fully closed cell isolation system for GMP-compliant cell production and cell sorting applications. The innovative system design provides superior cell isolation along with ease of operation, with unparalleled flexibility that enables a smooth transition from process development to cell production.

Bovine serum albumin (BSA) is used extensively as a carrier protein to dilute antibodies and as a general protein blocking agent in immunoassays and immunodetection protocols. Our IgG-free BSA, which is also protease-free, should alleviate many of the problems associated with using BSA. Many preparations of BSA, even some of the highest purity grades, contain IgG that may become an antigen for cross-reacting secondary an…

ChromPure is our trade name for highly purified proteins from the serum of non-immunized animals.

Antisera to Enzymes, Serum Proteins, & Whole Serums. Polyclonal antisera from immunized hosts are lipid extracted to improve clarity, salt fractionated, dialyzed against phosphate buffered saline containing sodium azide, and freeze-dried. Antisera against whole serums are obtained by immunizing host animals with whole serum. Antisera against whole IgG molecules [i.e. Anti-IgG (H+L)] are recommended for bridging PAP to prima…

Solid-Phase Immunoadsorbent Gels. Highly purified IgG from the serum of non-immunized animals is coupled to cyanogen bromide-activated 4% agarose gels for use in preparing affinity-purified antibodies or removing cross-reactive antibodies. Proteins are coupled at a concentration of 1 mg protein per ml of settled gel, and are packaged in phosphate buffered saline with sodium azide.

Peroxidase-Anti-Peroxidase (PAP) Soluble Immune Complexes. Whole antisera against IgG (H+L) are recommended for bridging PAP to primary antibodies. Antisera against IgG (H+L) or against the F(ab') 2 fragments of IgG will also bridge PAP to IgM primary antibodies (such as IgM monoclonal antibodies) by virtue of common light-chain recognition.

Anti-His Tag antibodies enable the detection of PolyHistidine Tags, allowing his-tagged proteins to be detected using a variety of techniques, including Western blotting, ELISA, Flow cytometry, and Immunofluorescence. 

Jackson ImmunoResearch AffiniPure-VHH™ Secondaries are polyclonal VHH Fragment antibodies (nanobodies) produced in Alpacas.

The all-around LNP process developer