Biotage Products & Reviews

ISOLUTE® Phase Separators streamline liquid-liquid extraction by eliminating the need for separatory funnels and drying agents. They reduce emulsion issues, save time, and minimize extraction waste, making sample work-up faster and more efficient.

TurboVap® evaporators automate nitrogen blowdown for fast, efficient solvent evaporation—up to 10x faster than traditional methods. With flexible configurations and modular manifolds, they handle diverse sample volumes and applications including SVOCs, pesticides, PCBs, and PAHs.

Expedite your reactions and make more molecules, cleaner and faster.

Biotage® Extrahera™ is an automated positive pressure workstation for column-based sample preparation in food and environmental testing. Supporting PFAS, pesticides, PCBs, PAHs, mycotoxins, and more, it handles 2 µL–50 mL volumes in plates or columns with dual-flow processing, precise pipetting, and GLP compatibility for reproducible, high-throughput results.

Accelerates solvent removal, evaporating even difficult solvents like water and DMF at 1 mL/min under moderate temperatures. With software-controlled vacuum for efficient solvent capture and a chemically resistant design, it enables rapid, reliable evaporation across a wide range of solvent systems, including peptide cleavage cocktails.

ISOLUTE® SLE+ plates and columns enable efficient supported liquid extraction of analytes from whole blood, plasma, serum, urine, and oral fluid. The simple load-wait-elute method delivers 99.9% removal of proteins and phospholipids without offline steps, offering superior recovery, reproducibility, and cleaner extracts than liquid-liquid extraction.

Provides consistent positive pressure for parallel processing of 96-well plates and 1, 3, and 6 mL columns. Ideal for SPE, protein precipitation, and supported liquid extraction, they ensure uniform flow, reproducibility, and efficiency—even with viscous samples.

PhyTip® columns use dual-flow chromatography within pipette tips to automate purification workflows. This technology delivers high reproducibility and exceptional sample purity for efficient, reliable results.

ISOLUTE® PLD+ Plates and Columns streamline LC-MS/MS sample preparation by efficiently removing proteins and phospholipids from plasma and blood samples in just three simple steps, ensuring high analyte recovery, enhanced sensitivity, and smooth processing with vacuum, positive pressure, or automated systems.

Previously known as SPE-DEX ® 3100

Previously known as SPE-DEX ® 5000

The Biotage® Selekt family of flash chromatography systems combines patented gradient development software with flexible fractionation strategies for streamlined purification.

The TurboVap® 96 Dual combines two independent evaporation systems in one compact unit, enabling simultaneous or separate method runs for unmatched flexibility. With intelligent evaporation control, dual heating, and adaptable plate formats (24, 48, or 96), it delivers faster, more consistent results while minimizing gas use.

Fully automated sample preparation system for PFAS and environmental workflows

Biotage® VacMaster™ Sample Processing Manifolds allow samples to be processed simultaneously under vacuum. Easy-to-use vacuum controls provide excellent sample flow control, leading to reproducible, reliable extraction conditions.

ISOLUTE® PLD+ for PFAS enables fast, simple “crash and filter” sample clean-up without conditioning or washing steps, delivering matrix-free extracts for accurate LC-MS/MS quantitation. Designed with low-background components, it ensures reliable PFAS recovery from complex biological samples.

Solid-phase extraction solution for bioanalysis of therapeutic oligonucleotides

EVOLUTE® PFAS SPE columns deliver high, reproducible recoveries of PFAS analytes with high-purity WAX sorbent and low-background components to prevent contamination. Available in 50 µm and 30 µm formats for compliance with ISO and EPA 533 methods, they are ideal for both manual and automated workflows.

Lyse or homogenize the toughest samples in seconds. Biotage® Lysera is an advanced, easy-to-use bead mill homogenizer designed for rapid, efficient grinding, lysing, and homogenizing of diverse biological samples. With a compact front-loading design, 99 programmable settings, temperature monitoring, and a wide range of accessories, it delivers reproducible results for any sample type without downtime between runs.

Biotage® Lysera is an advanced automated bead mill for rapid homogenization and liquid extraction in food and environmental testing. Featuring a space-saving front-loading design, 99 programmable settings, temperature monitoring, and versatile bead kits, it efficiently processes diverse sample types and sizes without cool-down, ensuring reproducible, high-yield results.

Biotage® Extrahera™ Peptide automates sample workup with precision and ease. Designed for synthetic labs, it enables automated solid phase extraction (SPE) and catch-and-release purification of up to 96 samples simultaneously. Positive pressure processing and complementary consumables ensure consistent, high-purity peptide samples free of catalysts and excess reagents.

EVOLUTE® Sample Preparation products feature advanced water-wettable polymer-based sorbents that deliver clean extracts and consistent analyte recovery for accurate LC-MS/MS quantification. Designed to minimize ion suppression and matrix effects, they provide reliable performance across a wide range of acidic, basic, and neutral compounds.

Biotage® PeptiPEC-96 High Throughput Kits streamline peptide purification with the automated PurePep® Easy Clean (PEC™) catch-and-release strategy. Purify 96 peptides simultaneously while removing impurities efficiently for cleaner, higher-quality peptide libraries.

Biotage® PeptiRen-96 well plates streamline peptide library workflows by enabling simultaneous post-synthesis clean-up of 96 crude peptides. Featuring reversed-phase media optimized for peptide SPE, they provide an efficient, automatable solution for rapid enrichment and preliminary screening.

The Biotage® Initiator+ Alstra™ simplifies solid phase peptide synthesis with an intuitive interface for easy, customizable workflows. Step-by-step programming, robotic reagent handling, and patented oscillating mixing ensure precise delivery, consistent performance, and uniform resin distribution—delivering accurate, reproducible results for peptides and peptide-like compounds.