Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap™ Mass Spectrometer by Thermo Fisher Scientific

Manufacturer Thermo Fisher Scientific  |   Model: IQLAAEGAAPFALGMAZR
4.6
/
5.0
  |  6 reviews
Identify, quantify and confirm more compounds rapidly and with confidence using the Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap Mass Spectrometer. 


Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap™ Mass Spectrometer by Thermo Fisher Scientific product image
Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap™ Mass Spectrometer
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Average Rating: 4.6
6 Scientists have reviewed this product

5 out of 5
Ease of use
5 out of 5
After sales service
4 out of 5
Value for money


  • Status:

    Reviewer
  • Member since: 2018

  • Organization: University of Illinois at Urbana Champaign



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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An excellent investment for your lab if you want fast and reliable results.
Rating: 4.7

  • Application Area: Metabolite analysis

"I use this instrument at my university campus, and I love it. Recently I've used it to analyze my samples using Compound Discoverer, metabolite analysis software also from Thermo Scientific which has makes my life much easier. Highly recommend this mass spectrometer and compound discoverer software if you want to analyze metabolites in your samples."

Review date: 18 May 2020 | Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Pfizer



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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It is a great piece of equipment but needs some software improvements.
Rating: 4.0

  • Application Area:Extractables & leachables

"It gives amazing data for unknown impurity identification as well as for confirming the identity of impurities. The sensitivity of the equipment is very good without losing resolution. The software (Xcalibur) needs improvement in terns of GMP standards and ease of use."

Review date: 02 May 2020 | Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: UIC



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Instrument is very stable and trustworthy.
Rating: 4.7

  • Application Area:Protein analysis

"Reproducible, clean data and easy to maintain. I also like the software for data anaylsis. User-friendly."

Review date: 06 Mar 2020 | Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: University of Illinois at Chicago



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great, easy to use instrument
Rating: 5.0

  • Application Area:Analysis of proteomics using mice brain tissue samples

"This provides high quality data. The resolution is really high, so we can analyse proteins in the globules in mice cerebellar samples. Overall, it is easy to handle and provides very high quality data."

Review date: 27 Feb 2020 | Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: Centre for Addiction and Mental Health



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great product.
Rating: 5.0

  • Application Area:Drug screening

"Very efficient for drug checking and screening services."

Review date: 06 Dec 2019 | Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: University of Milan, DeFENS



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    3 out of 5
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I cannot imagine MS without the high resolution and without our Q Exactive!
Rating: 4.3

  • Application Area:Food science

"Q Exactive allowed us to make a significant step forward in our research. It changed our approach to MS analyses in food science."

Review date: 18 Feb 2019 | Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap™ Mass Spectrometer

High-Confidence Results, Quickly

  • HRAM and full-scan capabilities capture all sample data, all the time, enabling retrospective data analysis without need to re-run samples
  • Resolving power up to 140,000 FWHM eliminates isobaric interferences, increasing confidence in results when analyzing samples in complex matrices
  • Better than 1ppm mass accuracy in full-scan and all-ion fragmentation (AIF) modes ensures confident compound identification
  • Fast scanning at 12hz and spectral multiplexing suited to UHPLC applications
  • Rapid polarity switching maximizes information obtained
  • AIF and multiple dissociation techniques—in-source CID and HCD—aid in compound identification
  • Extended mass range to 6,000m/z enhances detection of singly charged small molecules and biomolecules
  • More than four orders of magnitude intrascan dynamic range, along with femtogram-level sensitivity, allow detection of trace-level and high-abundance compounds in the same scan

Greater Confidence for Drug Discovery and Metabolism Studies

  • Triple quadruple-equivalent ability to quantify parent compounds and metabolites along with identity confirmation provides greater throughput
  • Fast HRAM Orbitrap technology eliminates interferences for high-confidence metabolite structural identification and large-scale profiling of metabolomics and lipidomics samples
  • Fast scan-to-scan polarity switching in both MS and MS/MS modes maximizes metabolite detection and identification from a single injection

More Information for Superior Proteomics

  • HCD yields superior fragmentation and higher-quality MS/MS spectra compared to CID, improving identifications
  • High spectral quality and a wide dynamic range make it possible to identify and quantify proteins other instruments cannot find.
  • Quan/qual capability make it easier to transition from proteomic discovery experiments to targeted protein quantification

Highly Specific Environmental and Food Safety Analyses

  • Specificity exceeding triple quadruple Q-TOF or Q-Trap levels make this mass spectrometer the preferred quan/qual screening platform
  • Data-dependent, full-scan MS/MS capabilities and HRAM data ensure the highest possible confidence in every identification

High-Confidence Quanfirmation for Clinical Research and Forensic Toxicology

  • The combination of SRM and HRAM capabilities provides high-confidence quanfirmation of endogenous steroids, drugs of abuse and pain-management therapeutics with ease.

Application-Specific Software for Greater Throughput

  • Thermo Scientific™ ExactFinder™, LCQuan™, Mass Frontier™, MetQuest™, MetWorks™, SIEVE™ and TraceFinder™ software are available to speed data analysis.

Product Overview

Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap™ Mass Spectrometer by Thermo Fisher Scientific product image

Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap™ Mass Spectrometer

Manufacturer Thermo Fisher Scientific

4.6 / 5.0 | 6 reviews