Prometheus NT.48 for protein stability by NanoTemper Technologies

"High quality and reproducible data, high throughput and best customer service."

"Gives us reproducible data, consistently. No sample prep is needed which saves time."

"Prometheus is very reliable and easy to use instrument that is delivering very high quality results, for both small molecules and biologics results. Its use is extremely time- and cost-effective. This instrument is one of the most used in our multi-disciplinary teams where we apply great number of biophysical instruments and dealing with >60 companies/vendors"

"The Prometheus NT48 is a very convenient way for us to test the efficacy of various chemicals that affect membrane protein stability. The small sample volume and relatively high throughput of the system makes additive selection for membrane proteins very easy."

"Our company 2bind uses the nanoDSF to optimize the formulation of therapeutic antibodies. The Prometheus allows us to screen 48 buffer conditions with a bit more than an hour. The antibody can be used as it is - without any modification - and in a very broad concentration range. Due to the capillary format the method consumes only low sample material. NanoDSF allows us to study thermal stability (Tm) and aggregation onset temperature within one experiment. The high data point density enables to see even smallest transition points. Output data are highly comparable to DSC, but obtained faster, with less material and less costs. The Prometheus device is very robust and occupies only small lab space. We can definitely recommend this technology as nanoDSF has become a standard application in our lab."

"The Prometheus solved a crucial step in our protein biochemistry workflow: we are able to quickly, efficiently and cost efficiently analyze the melting behavior of enzymes."