Precellys^® Evolution - Tissue Homogenizer by Bertin Instruments

"Easy to use, quick and effective, gives reproducible consistent results."

"Before this machine, I was using pestles to extract RNA from fibrous tissues, with poor results at the end. I needed 20 minutes per sample. Now I can extract up to 24 samples at the same time, with high reproducibility in only 20 seconds. Plus the machine is simple to handle!"

"Precellys Evolution is easy to set up and use. We have been using this homogenizer for six months and it has been very efficient and reliable. Creating methods is a breeze and after-process cleanup is also convenient."

"Overall, the machine is user friendly and easy to set up. Our biggest disappointment was that the Precellys will only work certain brand tubes, others didn't allow the vacuum to form and the machine didn't start with the tubes we frequently used in our lab so we had to switch the brand of lysis tubes. The results we obtained were great, great at lysing difficult to destroy animal tissue."

"Our lab purchased this homogenizer for metabolite extraction from animal tissue. We have been using it for a couple of years with no issue. It's a very powerful device that was able to crush any tissue sample that I have tried so far. It has a great deal of customization option to accommodate any type of sample as well."

"We are very happy with the equipment, we lyse cells, we lyse microbes, both to extract proteins and DNA to perform western blot, or sequencing. The lysis is very fast, and either protein or DNA is extracted with high quality. The results are reproducible."

"The Precellys Evolution or "Shaky Machine" as we call it in the lab has streamlined our protein and RNA isolation from adipose tissue and blood vessels. The quality of RNA isolated is routinely high and we use this RNA for sequencing and qPCR. Our machine gets fairly high usage, and Bertin has been great with customer service when parts need replacing. I can't imagine going back to using a Polytron for tissue processing or any other bead-based tissue disruption/homogenization machine."

"The system works great. It has been problem free since I began working with it two years ago."

"This instrument is very easy to use and gives me reproducible results. The customer sales team were also very helpful and gave me great advice for which tubes were going to give me the best results for my application. The instrument user guide is detailed and the user interface on the machine is also simple and clear."

"Extremely efficient tissue lysis, nothing better on the market!"

"Effective product to obtain perfect homogenized tissue. Easy to use even for non professionals. High quality product."

"The kit is very easy to use. After purchase technical support are very helpful. The quality of the extracted DNA/RNA from paraffin sectioned slides is usually very decent. Percellys Evolution maintenance kit contains all the external pieces to replace each year of use allowing to give the maximum life time to the equipment."

"Application: Tissue Homogenisation for Fresh Frozen Tissue <5mg. Results: High quality gDNA and RNA extraction from tissue. We used the precellys tube following the protocols written on precellys.com to homogenise the tissue sample we received. The tubes worked perfectly for our application. Reproducible results and easy to use. Next time we would order clear tubes over opaque. Highly recommended."

"Easy to use, many kits available for different sample types, quick aind consistent results"

"We have been able to achieve rapid and reproducible extractions from livers for the analysis of a multitude of metabolites. The processing power and capabilities of the Precellys setup is not just an advantage in terms of a more streamlined and rapid experimental workflow, but is also of great value when dealing with the analysis of short-lived metabolites."

"Easy to use, fast and very reliable. It would allow us to work with small amount of tissue, which is precious and limited sometimes. The RNA quality is very good."

"The product really stood out. We are really happy with the purchase"

"This is a compact easy to use centrifuge, and really saves space on my lab bench compared to my old huge one."

"We use the instrument for grinding of plant samples that we want to extract DNA or RNA from. It is also being used for soil samples and filters from air or water samples. Because all different sizes of tubes and different bead-types it can be used for all kinds of materials. We will also purchase the Cryolys system."

"It is very easy to use. I find it very convenient and user friendly. High quality sample processing."

"Yes. High quality and efficiency. It save you time and money eventually."

"It was easy to use. The price of beaded tubes is really high. I always got great RNA quality after using this machine"

"Very efficient and essay to use. Gets the job done."

"Excellent product. Performs as expected. Highly recommended."

"Very good piece of equipment that functions well. I would say the purchase price is a bit high... That is why I gave it 4 out of 5 stars"

"Efficient way to extract metabolome from biological systems with a high reproducibility and efficiency. Easy to handle and handy to install any place including BSL3 high containment laboratory. We currently have two systems normally being operated in both wet lab and BSL3 with great satisfaction."

"Very efficient in breaking tough-to-lyse bacterial cells (Mycobacteria, Bacillus endospores, etc) for RNA/DNA/protein extraction. Also very simple to use. For temperature-sensitive samples, care in terms of sample temperature must be taken (keep in ice in between cycles). The manufacturer sells an extra equipment to cool down automatically, but the price is still not competitive. In general, a very good piece of equipment."

"Easy to use, configurable and with reproducible results. It is very versatile, covers all applications and can be used or configured for use with different sizes of tubes. It is the ideal tool for homogenization."

"Product was easy to set up and use right away. I was able to get the desired results with next to no hassle."

"The instrument is quite easy to use. The website in terms of finding protocols for different applications is a bit unwieldly"

"It it a flexibility and modular machine. This product offers a lot a advantages and the support with the dealer and application centre is a solution in gold."

"Easy to use / Still on evaluation / Flexible apparatus that will be used in various applications"

"So easy to use and to maintain ! Easy and fast to grind all kind of tissue."

"Easy of use. Standard and consistent results. No problem noted and no reparations needed over the past few years."

"Very quick, homogenisation, good quality of RNA and Protein."

"Easy programmable tool, very efficient and wide range of possibilities. Perfect for our applications in nanotechnology for medicine. We had an internal issue completely unusual with this machine, they exchanged it next day with a perfectly working one. They also offer a very relevant expertise."

"The precellys Evo is a great instrument for our needs, it is very easy to use and we are able to control the temperature depending on the assay that we are running. It is not as loud as the gino grinder still very efficient at homogenizing all sorts of tissues. We have had the Evo for less than a year and it is used frequently. We have not had any issues with the machine or the cooling container. Temperature control can be tricky when homogenizing for a long period of time. The temperature does drop rather quickly and samples do run the risk of freezing. We have been able to avoid this, so far."

"The equipment is easy to use. Extraction procedures are fast and reproducible. After sale, information on new applications were available on the webpage and also by the product managers."

"Easy to use and reliable. sometimes can have a bit of hiccups in the release of the lid."

"Cytosol extraction on breast cancer tumor, run for maximum samples in one step. No cross contamination, reliable, easy to use and high performance extraction."

"This homogenizer is very easy to use and has been excellent across a range of tissues. The accessories available ensure that I can use it for all purposes."

"The Precellsy is very easy to use, providing fast homogenisation of samples, and allowing processing of large sample numbers instantly. Homogenisation is standardised for samples allowing for consistency when samples are processed on multiple days. RNA quality from samples processed in this manner consistently have high RIN scores (>9) even with difficult tissue, such as those from the gut/liver. In addition the Precelly is substantially safer than hand held homogenisers, which require trizol tubes to be open, this allows for a closed system of homogenising, thus improving safety for users. I'd highly recommend any lab with large levels of RNA work to be done, invest in this product."

"It is easy to use. Actually we are doing the first tests but it is very reliable."

"This instrument is really perfect. If you use right beads for homogenization you get really perfect results. I usually homogenize grapevine trunks and leaves and I get always best results for both of them."

"The instrument is very easy to use. It can simultaneously process upto 24 samples. It saves a lot of time. Sample to sample variability is less. Its a bench top instrument, so handling is quite easy."

"The instrument enables to obtain reproducible results in western blot experiments, for the evaluation of the expression of the protein of interest in tumor tissue samples."

"It is quick, safe and efficient! The most exciting feature is that you can connect it with Cryolys and process your heat-labile samples (such as RNA samples) with ease. I cant imagine myself handling so many fungal samples for my genomics project so efficiently without the help of Precellys® Evolution. Thank You Bertin!"

"I was shocked by how instrument's ability to provide such reproducible results and the fast reaction times when comparing to other instruments."

"It is easy to use, high quality and good value for money."

"The precellys Evolution is an easy to use sample homogenizer that helps to achieve reproducible results of high quality."

"Simply an amazing versatile and excellent equipment to optimize the work of the laboratory."

"The product is very simple to use and it has a great best cost-benefit ratio."

"High quality in the homogenization of hard tissues like meat"

"We have homogenized tissue samples from 1 gram to biopsy samples and got a great results. It is very flexible and easy to operate."

"This is an excellent equipment. One of my favourite. It reduces the time required to complete an experiment by a significant margin."

"We bought this device to replace our old Fast-prep. We also included the cryolis option, in order to keep our samples at a reasonnable temperature. With the cooling system, we don't need to take out the samples to put them on ice to chill anymore. This saves a lot of time. We also took more racks to enable fast unloading/loading of the samples. The system is really easy to use and we are really happy with it. There a few minor details, however, that could be mentionned : - the closing system cold use some improvements. With the vibrations generated, some screws from the lids started to move. The support team reacted really quickly when we mentioned it. - the cryolis is a bit strange because turning it off doesn't completely stop the flow of cold air. So we play with the compressed air valve to stop the cooling"

"The instrument has proven to be an essential part of my projects. It is easy to operate and program. Animal tissues are uniformly homogenised, aiding the culture of bacteria residing within them."

"The Precellys allows very significant time savings compared to conventional techniques. Indeed, in our case it allows the simultaneous processing of our cohorts. In addition, our extractions have quality and yield equivalent techniques that we used previously. Finally, easy and secure use allows all users (including novices) to use it without prior training"

"The Precellys allows a very significant time savings compared to conventional techniques. Indeed, in our case it allows the simultaneous processing of our cohorts. In addition, our extractions have quality and yield equivalent techniques that we used previously. Finally, easy and secure use allows all users (including novices) to use it without prior training."

"The real performance of this machine is not like your claim (can't fully homogenize the tumor sample)! And it's not easy to use! The price is not friendly!"

"It is easy to use although when we had a problem we have not found anyone giving us a good idea. We also had problems with the consumables (tubes) and there was not a satisfactory answer either."

"Product is used for robust and reliable tissue homogenization. It's a great product but the website is not very easy for quickly finding the relevant protocol for different tissues. "

"High quality chemicals are not so easy to use. Success is our moto. "

"Avoiding contamination from different samples, precellys have good consumables. High speed and adjustable frequency. When in RNA extraction processes, few time in operation is better. "

"Precellys is an innovative way of extraction, using high frequency shacking for sample extraction. I found it efficient, fast, reproducible and easy to use. Our samples were: epidermis and dermis I recommend this equipment for at least these samples. "

"It has a good efficiency working with DNA extraction of teeth and bones"

"The equipment is ease of use and fast, and the best part of it that you can have up to 24 samples at once and very homogenous between them."

"It is very helpful in mincing the hard tissues. It made our work in tissue homogenization very efficient, so we can deviate from using mortar and pestle which takes at least 30 minutes per samples. but now I can perform homogenization for at least 24 samples in 3 minutes. with the use Precelly beads, tissues were homogenized faster and can avoid contamination. Every molecular biotech should invest on this equipment. It is better to use it with the recommended Precellys’ beads because they really work the best to wide range of tissues. After sales care are very supportive online because of the very active customer service and local suppliers who are very prompt to answer our concerns. I have been using it since I was doing my graduate thesis in plants and now that I am working on livestock, these are still worth of having in the lab!"

"With the use of the Precellys Evolution homogeniser, we have been able to increase the sample throughput and accuracy when analysing the metabolome from environmental microbial samples. We have the found the Precellys Evolution to be extremely easy to use and reliable. The instrument comes with a number a predefined methods already programmed, plus it has the added ability and flexibility to customise additional methods."

"Easy to use (vacuum block system, key pad) Great grinding efficiency for dried bean/rice/pepper seeds, frozen cabbage leaves. Good to be repaired in the domestic when a breakdown. Before grinding for frozen cabbage leaves, placed the tubes and beads in LN2 for frozen. So it should get a cabbage leaf in the powder state without cooling system. "

"Homogenize various tough tissues effectively and efficiency using Precellys 24-Dual without having laborious preparation steps. Our laboratory has been using the Precellys 24-Dual as an alternative method to our conventional methods for sample preparation for proteomic analysis. We also found high reproducibility versus our conventional methods as well as reproducibility between different tube and bead types. Extraction of proteins from no matter what the sample type is easy and everyone loves using this great and compact homogeniser. It has been three years we are using this machine regularly and noticed no trouble at all. Although no service or repairing was required but supplier is always in touch making sure everything is going OK. It is a highly recommended instrument for those who are having troubles extracting proteins from tough tissues or samples."

"This equipment is easy to use. We can process more samples per cycle (There is not wait time between process cycles) and it does not heat the samples as much as previous versions. I like that it can hold the bigger 15 mL tubes."

"Good and easy to use Highly efficient Satisfaction Increased sensitivity "

"It is very effective and easy to use. I found reproducible results."

"Easy to use! Highly reproducible results. Simplifies procedure. "

"The product is quite good. My results are clear and replicable."

"With this team we have obtained reliable and reproducible results, and most importantly in less time is possible to obtain high quality nucleic acids."

"It was easy to use and gave us reproducible results. I am not sure for the efficiency as we did not do direct comparison experiment."

"> Very easy and simple to use. Perfect for daily extraction in clinical setting. > Significantly improved my extraction yield. Important for tiny clinical samples. > Works great on various sample types (tumor types, cell lines,...) and for diverse applications (DNA, RNA). > Minimum time for instrument validation in diagnostic lab."

"Very high quality and reproducible. Easy workflow for multiple samples with no contamination."

"This machine has been of the best instrument we bought within the last few years. It is really easy and fast to use, and it has tremendously increased the productivity of our lab, saving us a lot of precious time. Since we started using this homogenizer for tissue samples disruption we routinely obtain high-yield and high-quality RNA which is essential for further gene expression analysis by the RT-PCR assays."

"Our lab has been very pleased with our Precellys instrument. It has performed flawlessly, and it was very straightforward to "tune" it to our desired specifications."

"The Precellys cuts down our sample processing times considerably and it homogenizes much more thoroughly than our previous methods. I love that the sample sizes can be smaller, which also means it saves solvent. Works great for pesticides from vegetation! "

"It's quite effective, fast and easy to use for my applications. We always get consistent data."

"Easy to order. Good to use. Reasonable price. Sales are responsible. "

"High quality of data, reproducible, validated. The use of the homogenizer is very easy. "

"Precellys is incredibly easy to use and has reduced our tissue processing time by at least 10-fold!"

"Easy to use. Gives good results and is highly efficient."

"My results are leaps and bounds better than before. The ease of use has freed up more time for experimental design so I’ve been able to progress further and faster than ever before. "

"The instrument is easy to use, easy to replicate settings and is a tool critical to the lab."

"It is easy to use. Facilitate my work for lipid extraction. The homogenization of different kind of tissues/organs is awesome."

"This equipment is very easy to use. The results obtained were of good quality and they help for publication."