SelectScience
Join Free
NewsLife Sciences

8 lab products making an impact in biomarker research

SelectScience

From immunoassays and ELISAs to multi-mode microplate readers, discover the technologies making a difference for other scientists in your field

11 Dec 2020
Edward Carter
Publishing / Media

Editorial article

Here at SelectScience, our goal has always been to provide scientists worldwide with the information they need to make the best purchasing decisions to advance their work. But we couldn't do that without the support and input of our vast community of reviewers. Here, as part of our new Biomarker Research Special Feature, we pull together a selection of our favorite reviews of technologies involved in biomarker research. Find out why these products have been recommended by your peers and see how they could help improve your own workflows!

1. All-in-one microplate readers

Achieve easy-to-perform low-volume absorbance assays with speed and flexibility with BMG Labtech’s SPECTROstar Nano Absorbance Plate Reader.

2. Highly efficient tissue homogenizers

Improve the robustness, safety, efficiency and flexibility of your DNA, RNA, proteins, drugs & metabolites extraction. The Precellys® Evolution by Bertin Instruments is a universal tissue homogenizer that provides high flexibility and high efficiency for either routine or R&D projects.

3. Highly reproducible immunoassays

Ella by ProteinSimple is a next-generation ELISA that boasts sub-picogram level sensitivity and more than four logs of dynamic range. In just 90 minutes, you get highly reproducible validated assay data with no manual steps.

4. Easy-to-use ELISA kits

Quantikine Colorimetric Sandwich ELISA Kits by Bio-Techne are complete and ready to use. This immunoassay is able to measure a range of molecules including cytokines, chemokines, growth factors, proteases, and more.

5. Powerful monochromator-based microplate readers

The CLARIOstar Plus Multi-mode Microplate Reader from BMG LABTECH is equipped with LVF MonochromatorsTM, spectrometer, and filters. Patented LVF Monochromators™ include cutting-edge technology, such as linear variable filters and a linear variable dichroic mirror. These provide flexibility while delivering filter-like performance for fluorescence and luminescence assays including fluorescence RET and bioluminescence RET.

6. High-resolution identification

The Octet HTX by ForteBio utilizes bio-layer interferometry (BLI) enabling label-free detection for protein quantitation and kinetic characterization at high speed and throughput. The HTX can measure up to 96 samples simultaneously, allowing both unlimited characterization capacity for various applications and custom assay tailoring to maximize analytical throughput or sensitivity and preventing bottlenecks.

7. Effect and reliable western blotting

FluorChem imagers by ProteinSimple are versatile — the FluorChem R possesses true multi-mode capabilities, with UV fluorescence, white light, chemiluminescence, visible fluorescence, and infrared fluorescence imaging, all in one compact system. Cover all your application bases in your lab with one easy-to-use system.

8. Multi-purpose fluorescent microplate reader

The POLARstar Omega by BMG Labtech is a multi-mode microplate reader designed to perform all plate-based assays, including fluorescence polarization (FP) experiments. Having simultaneous dual emission (SDE) detection, it can capture two emission wavelengths at once, like the perpendicular and parallel signals in FP.

These are just a few of the available products that have helped your peers and could make an impact in your laboratory. For more reviews of technologies in your field, visit our product and reviews directory or leave your own review today and help other scientists level up their equipment and consumables.


SelectScience fulfills a longstanding need in the scientific community: a well-organized, centralized resource of thorough, unbiased reviews of a wide range of scientific instrumentation and products. The ability to factor in opinions and direct experiences of end-users saves money, time and a lot of potential headaches

Dr. Thomas Pisanic  Johns Hopkins University


Learn more about why other scientists leave and read product reviews >>

Find the latest protein biology news and resources in our Biomarker Research Special Feature>>

Related products

Request Quote for All Products

Links

SelectScienceCompany website

Tags

Western BlottingWestern blotting equipment is used to transfer and identify specific proteins within a sample, reveal protein modifications, as well as give a semi-quantitative estimation of their concentration. Western blotting equipment includes all apparatus necessary to transfer proteins from gel to membrane and subsequent processing steps. Protein transfer can be performed by electroblotting with wet, semi-dry and dry transfer systems onto nitrocellulose and PVDF membranes. Blocking, washing and labeling of membranes follows, involving buffers, blocking reagents, blotting / incubation trays, labeling reagents, immunoblotting assays, antibodies and conjugates. Automated equipment for these steps is available to accelerate your lab workflow. Finally, detection and imaging of proteins can be conducted using gel documentation and imaging systems. Find the best western blotting equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell Adhesion AssaysCell adhesion assays are used to quantitate attachment and analyze the molecular mechanisms for extracellular matrix adhesion, cell migration and sensitivity to inhibitors. Find the best cell adhesion assay equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.DNA / RNA Extraction and PurificationPurified DNA and RNA are required for numerous downstream molecular biology applications. Consequently, the importance of high-quality DNA/RNA extraction and purification equipment cannot be underestimated. Many purification kits are available and are typically optimized for nucleic acid type and source, including plasmid DNA, genomic DNA, mRNA, RNA and viral nucleic acid purification kits. Automated extraction and purification of nucleic acids can be implemented with magnetic bead separator instruments or high-throughput purification workstations. Find the best DNA/RNA extraction and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.DNA SequencingDNA sequencing, such as sanger sequencing, is a biological technique that determines the precise order of nucleotide bases in a fragment or template of DNA. DNA sequencers and genetic analyzers are based on capillary electrophoresis, where labeled DNA fragments are electrophoretically separated by size as they migrate through a polymer. Find the best DNA sequencing products, including DNA sequencing kits, genomic libraries and genetic identity kits in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :ElectrophysiologyElectrophysiology is the study of biological voltage changes, from a single ion channel through to a whole organ scale. Voltages can be measured using patch clamping, automated workstations, electrophysiology rigs or cell based assays. Specific cell lines, manipulators and microinjectors are also available for electrophysiology research.DNA / RNA QuantificationDetection and quantification of nucleic acids is important in molecular biology, cloning, expression, forensics and clinical diagnostics. Nucleic acids can be detected by labeling with colorimetric, fluorescent or radio labels and using in situ hybridization kits to identify specific sequences. Multiple nucleic acids can be detected and quantified at once using RNA / DNA detection beads or RNA / DNA microarrays. Find the best DNA / RNA Quantification products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ImmunoassayImmunoassays are laboratory tests that utilize antibody-antigen interactions to detect specific substances. They are widely used in diagnostics for detecting diseases, drug testing, and environmental monitoring. These assays offer rapid, sensitive, and precise detection of biomarkers, making them invaluable in clinical and research labs. Browse our peer-reviewed product directory to compare immunoassay systems, read user reviews, and get pricing directly from manufacturers.Microplate Reader SoftwareFluorescenceThe emission of fluorescence occurs when a photon of energy is supplied to a fluorescent chemical compound by an external source, causing it to become excited. Fluorescence can be detected and measured for different purposes using microplate readers, fluorescence microscopes, fluorescence scanners, and flow cytometers.ELISABiomarker DiscoveryClinical biomarkers refer to substances related to known medical conditions that can be accurately measured <i>in vitro</i>. Biomarkers can be used to diagnose presence of a disease and indicate disease severity. The discovery of new biomarkers is incredibly valuable in the field of diagnostics.

Related articles