Ella Automated Immunoassay System

In this application note, Bio-Techne introduces Simple Western™, an advanced immunoassay platform that overcomes the limitations of traditional ELISA. Unlike ELISA, Simple Western employs capillary electrophoresis and adds the dimension of molecular weight to protein analysis, providing sensitive, accurate, and reproducible quantitative immunoassay read-outs. While ELISA offers a two-dimensional measurement of antibody binding, Simple Western adds a third dimension by simultaneously measuring antibody binding activity and providing molecular weight size information. This innovative approach enhances the depth and accuracy of protein analysis under varying experimental conditions.

T cell-based therapies hold dramatic potential for treating intractable diseases by redirecting the power of living immune cells. The in vivo performance of cell therapies will improve with deeper understanding of cellular behavior, while technological advances contribute to process efficiency, scalability, and safety. In this eBook, explore several of the biological and manufacturing challenges for T cell therapies and discover how Bio-techne's solutions can help overcome these obstacles at each process stage.

In recent years, the emergence of cell therapy technologies has piqued great interest from researchers and clinicians seeking to develop targeted age-related macular degeneration (AMD) cell therapies. Through cell therapy, functional retinal pigment epithelium (RPE) cells can be transplanted into a patient’s eye to prevent the loss of photoreceptor cells and thus halt the progressive loss of vision. In this whitepaper from Bio-Techne, explore the current landscape of AMD cell therapy, and examine the future prospects and challenges for this exciting emerging technology.

Neurofilament light (NF-L) has emerged as a biomarker for diagnosing and monitoring the progression of a variety of neuropathies such as Huntington’s disease, amyotrophic lateral sclerosis (ALS), Alzheimer’s disease, and multiple sclerosis. The Simple Plex NF-L Assay on Ella delivers the sensitivity required to measure NF-L with a high level of reproducibility in serum, plasma and CSF sample types. This application note demonstrates the Simple Plex NF-L Assay’s ability to distinguish between normal and disease state samples.

Immune checkpoint molecules play a central role in regulating the activities of different immune cell types. This eBook by Bio-Techne details some of the current and emerging immune checkpoint molecules that are being investigated as potential targets for cancer immunotherapy.

Immune cell therapy has revolutionized the way we think about treating cancer, but could this type of immunotherapy be beneficial in an infectious disease setting? The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) and its associated coronavirus disease 2019 (COVID-19) has certainly presented researchers with an opportunity to evaluate its therapeutic utility.

Catch up on this on-demand webinar to explore potential biomarkers for COVID-19 severity and learn how the early assessment of viral load in plasma could improve patient care

Explore topics from in vitro diagnostics and advances in COVID-19 sample prep to neonatal hypocalcemia and cytotoxicity assay development

Explore topics from therapeutic antibodies and advances in COVID-19 sample prep to neonatal hypocalcemia and cytotoxicity assay development

From immunoassays and ELISAs to multi-mode microplate readers, discover the technologies making a difference for other scientists in your field

Trends in biomarker discovery methods and novel techniques advancing research, clinical diagnostics and therapeutic development

Exclusive interviews, free downloads, the latest methods and much more to help support your immuno-oncology research