Best Practices for Tough Sample Grinding in Molecular Biology Using Precellys

The biggest challenge when working with fibrous, elastic and tough samples is efficient sample processing. Furthermore, generation of heat causes degradation and denaturation. Here, Bertin Instruments describes the improvement of extraction yields of tough samples using the Precellys^® evolution homogenizer, thanks to 3D-bead beating technology. When paired with the cryolys evolution cooling unit, this technology can also prevent degradation of heat-sensitive biological samples.