PAPP-A2 ELISA by Ansh Labs

Manufacturer Ansh Labs  |   Model: AL-109  |  Available Worldwide
Pregnancy associated plasma protein-A2 (PAPP-A2) is a novel metalloproteinase identified as a homolog of PAPP-A in the metzincin superfamily of pappalysins. PAPP-A2 shares 46% sequence identity with PAPP-A. PAPP-A2 is a noncovalently linked dimer of two 220-kDa subunits. It exhibits robust proteolytic activity against IGFBP-5 and possibly also IGFBP-3.  PAPP-A2 is expressed in a wide range of tissues and is abundant in placental syncytiotrophoblasts and the pregnant uterus.   

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The Ansh Labs' PAPP-A2 ELISA kit is a quantitative three-step sandwich immunoassay. It utilizes standardized recombinant human PAPP-A2 calibrators. The antibodies are highly specific and do not detect proMBP, dimeric PAPP-A, or PAPP-A-proMBP complex.

  • Analytical measureable range of 0.19 – 16 ng/mL allows for studies in a variety of physiological states
  • Sensitive to 0.71 ng/mL
  • Total 2.5 hour incubation at room temperature
  • Long shelf life of 24 months

For Research Use Only within the United States. Ansh Labs, located just south of Houston Texas, is an FDA registered manufacturer of diagnostic test kits, antibodies, antigens, and proteins.