NucleoCounter® Family of Cell Counters and Analyzers
NucleoCounter® instruments provide platforms for determination of viability and cell count as well as advanced image analysis of yeast, veterinary semen, insect cells and mammalian cells, both primary cells and cell cultures, including cells in aggregate or microcarrier cultures. These high precision instruments have become the golden standard in cell therapy and bioprocessing labs due to their precision and low variability…
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Great performance, I would not use any other cell counter!
Mammalian immune cell counts
The NC200 Nucleocounter is a high performance device which gives robust and accurate results, also showing high precision when performing cell counts for important human cell samples. I have been using it for the feasibility of my method verification of cell counting, and I really like how easy this equipment is to use and also the interface (the software is also very user friendly). The customer service is fantastic, very friendly equipment experts who can resolve all your doubts, I've had the best possible treatment, I would highly recommend using an NC200 for cell counting, I haven't experienced any other equipment that performs better than this.
Review Date: 14 May 2024 | ChemoMetec
Very good counting device, don't want to use another one anymore.
Cell counting human PBMCs and cell lines
Easy to use and fast. Highly reproducible results. Gives many parameters of counting results e.g. Total cell counts, viable cells, dead cells, vitality of cultured cells which are very helpful for documentation.
Review Date: 6 May 2024 | ChemoMetec
Great system, we use it daily and recommend to all of our clients
Cell therapy
The NC202 has simplified our cell count and viability processing, enabling smooth comparison between process development and GMP. The Chemometec team have been very supportive throughout our development and transition between the NC200, 250 and 202.
Review Date: 2 May 2024 | ChemoMetec
Great results, highly recommended
Cell counting
Equipment of high effectiveness and great customer support. We obtain high quality and reproducible results, very easy to use.
Review Date: 26 Apr 2024 | ChemoMetec
NC200, very good device and service support
Cell viability and count
We use the NC200 device for the viability and cell count because it's a device with a very good correlation with microscopy for primary cells (like CD34+ cells, T lymphocytes) but also for cell lines. At this moment, we work with new cells which have some big aggregates and we have discussed with French Chemometec people who have provided some possibilities to improve our results of viability and cell count.
Review Date: 19 Apr 2024 | ChemoMetec
Insect cells counting
Counting Insect cells cultivation
We used the cell counter for insect cell cultures growing in flasks. The counting method works well for this cell type. We obtained consistent and reproducible results even with high cell densities and some cell clusters. The use of cartridges enables safe analyses for the operators.
Review Date: 17 Apr 2024 | ChemoMetec
Highly recommended
Cell therapy
We use the NucleCounter NC-200 on a regular basis for counting various cell types (adherant or suspension cells lines, primary cells) both for R&D and bioproduction activities. This counter is easy to use and offers a very good reproducibility and reliability.
Review Date: 10 Apr 2024 | ChemoMetec
Easy to use.
Count PBMCs isolated from blood samples
The product was easy to use. The Via1 cassettes used to insert the samples in for measurement already contained the dye, making it easy to order and use.
Review Date: 8 Apr 2024 | ChemoMetec
Makes the day in the lab much faster
Cell counter
Nice and easy to use.
Review Date: 5 Apr 2024 | ChemoMetec
Very good results obtained, difficult to do without it. Trés bons résulats de compatge obtenus , difficile de s'en passer.
Automated counting for cell culture. Comptage automatisé pour mise en culture cellulaire
Good machine efficiency for automated cell counting, reproducible results, easy to use as fast and reliable cell counting is achieved. Bonne efficacité de la machine pour un comptage cellulaire automatisé, résultats reproductibles, facile à utiliser car on obtient un comptage cellulaire rapide et fiable.
Review Date: 1 Mar 2024 | ChemoMetec
NucleoCounter® instruments provide platforms for determination of viability and cell count as well as advanced image analysis of yeast, veterinary semen, insect cells and mammalian cells, both primary cells and cell cultures, including cells in aggregate or microcarrier cultures.
These high precision instruments have become the golden standard in cell therapy and bioprocessing labs due to their precision and low variability, easy to operate software interface, and scalability across the development and production pipeline with a 21 CFR Part 11- / GMP-ready software.
Automated cell counting:
- NucleoCounter® NC-202™
- NucleoCounter® NC-200™
Advanced fluorescent assays:
- NucleoCounter® NC-3000™
Sperm cell counting:
- NucleoCounter® SP-100™
Safe cell counting device:
- Via2-Cassette™
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NucleoCounter® SP-100™ sperm cell counter
ChemoMetecThe NucleoCounter® SP-100™ sperm cell counter offers unique ease of use and effective determination of total sperm concentration and viability in semen samples from ejaculates or extended doses. The NucleoCounter® SP-100™ is very simple to operate and the measurements can be performed by operators with only limited training in laboratory work. The compact instrument fits perfectly in any research, quality control or production site. The measurement range of the NucleoCounter® SP-100™ is virtually unlimited due to dilution prior to the analysis. The NucleoCounter® SP-100™ sperm cell counter was developed for samples from boar, stallions, and bulls, and has been used for research in a range of animals, including fish and goat. SP-100™. Key features: Easy operation 30 sec. analysis time No cleaning or calibration Maintenance and service free Excellent reproducibility No interference from gel particles in semen No interference from egg yolk or milk in extender
NucleoCounter® NC-200™ automated cell counter
ChemoMetecThe NucleoCounter® NC-200™ is a high precision automated cell counter utilizing state-of-the-art image cytometry. With user-adaptable protocols and specialized assays for counting a wide range of mammalian cells, including adipose-derived stem cells, T cells, aggregated cells and cells on microcarriers, the NucleoCounter® NC-200™ provides an all-in-one solution for cell counting and cell viability determinations. Samples containing cells are loaded using the Via1-Cassette™ which includes an in-built pipette and immobilized fluorescent dyes to stain the total and dead cell populations. With the Via1-Cassette™, all errors introduced during pipetting and staining are avoided. Also the Via1-Cassette™ is volume calibrated ensuring a high precision in determining cell count and viability. Analyzing one sample takes less than 50 seconds. The NucleoCounter® NC-200™ is designed to be easily implemented in GMP and 21 CFR part 11 compliant laboratories. The in-built protocols for IQ/OQ/PQ ensure control of consistent operation. Standardized pdf-reports, user control and audit trails allow for documentation of all events. Together with the high reproducibility and consistency in measurements, the NucleoCounter® NC-200™ is the ideal choice for automated cell counting in GMP and 21 CFR part 11-compliant laboratories. Our Field Application Scientists (FASs) provide training, service visits, installation and user guidance on-site or online to ensure you get the best start to working with the NucleoCounter® NC-200™.
NucleoCounter® NC-202™ automated cell counter
ChemoMetecThe NucleoCounter® NC-202™ automated cell counter is our 3rd generation cassette-based image cytometer. Featuring improved hardware and new NC-View™ software, we take precision, speed and data management to new levels. The NucleoCounter® NC-202™ is the most precise automated cell counter on the market: The combined inter-operator/inter-instrument variation is typically 5 – 10%. Consequently, you obtain identical results with any cell sample, recorded by any user, located anywhere in the world. The NucleoCounter® NC-202™ has one universal cell counting protocol that handles all cell types: No optimization is required. The instrument provides robustness and precision regardless of cell size, morphology and media type, even in the presence of red blood cells, magnetic beads or cellular debris. Consequently, the NucleoCounter® NC-202™ is easy to validate, even for the most complex processes. The all new DebrisIndex™ is a measurement of culture debris build-up. Debris negatively affects downstream filtering and purification steps, so a direct measurement of debris facilitates better process development parameters. The NC-View™ software is compatible with 21 CFR Part 11/GMP guidelines and can be integrated into your clinical workflow. Our Field Application Scientists (FASs) provide training, service visits, installation and user guidance on-site or online to ensure you get the best start to working with the NucleoCounter® NC-202™. What’s NEW – NucleoCounter® NC-202™: Automated cell counter Analysis time only 30 seconds Improved light sources for greater signal-to-noise ratio and dynamic range DebrisIndex™ monitors cell culture health and bioreactor production runs Broader linearity range: Count samples up to 1×107 cells/ml Instrument Service Plan: Keep your instrument up-to-date Automatic data quality checks for sample artefacts Electromechanical cassette slot for easy operation
NucleoCounter® NC-3000™ advanced cell analyzer
ChemoMetecThe NucleoCounter® NC-3000™ is an advanced image cytometer utilizing fluorescence imaging to characterize cell properties. The NC-3000™ can perform high-speed cell count and viability analyses and it includes plug-and-play analytical assays of mammalian, yeast and insect cells. Pre-defined assays include a unique 5-minute cell cycle assay, a selection of apoptosis assays and a GFP transfection efficiency assay. With the FlexiCyte™ license, you can create protocols choosing light source, emission filters and detailed settings. The accompanying NucleoView™ software can be used for data analysis of the results and has unlimited licenses. The NucleoCounter® NC-3000™ benchtop image cytometer ensures flow-like analysis with high reproducibility, and it is calibration-free. The NucleoCounter® NC-3000™ is ideal for the regulated QC, production and even PD and R&D departments. Instrument and method verification tools and 21 CFR Part 11-ready software ensures that the adheres to the requirements and demands of the pharmaceutical and biotech industries. Standardized pdf-reports, user control and registration of audit trails allow for documentation of all procedures. Combined with high precision and limited user influence this makes the NucleoCounter® NC-3000™ a one-of-a-kind cytometer. Our Field Application Scientists (FASs) provide training, service visits, installation and user guidance on-site or online to ensure you get the best start to working with the NucleoCounter® NC-3000™. Key features: No rinsing or clogging Easy to operate – no warm-up or calibration CFR 21 Part 11 ready Automated PDF reports Unlimited software licenses and free software updates Excellent support by field application specialists High-speed cell counting and advanced cell analysis Visual inspection of cells – plot to image Images are saved automatically and can be re-analyzed later Low sample volume Build your own assays with up to 4 analytical channels Export data to FCS Express, FlowJo, etc.