GloMax® Discover Microplate Reader
This ready-to-use multimode detection system includes: high-performance luminescence, fluorescence, UV-Visible absorbance, BRET and FRET, two-color filtered luminescence and kinetic measurement capabilities. The GloMax® Discover System is a high-performance multimode detection instrument developed with Promega reagent chemistries to provide a simple means of detecting advanced chemistries. This instrument provides…
Receive your quote directly from the manufacturer.
Indispensable piece of lab equipment.
Plate reader
Great plate reader, easy to use!
Review Date: 20 Nov 2020 | Promega Corp.
Great instrument!
NanoBRET and luminescence studies
This is an easy-to-use, efficient machine with a small footprint.
Review Date: 25 Oct 2019 | Promega Corp.
Great instrument
for biotech lab
High quality and great value for money. user is happy and has no complaints.
Review Date: 10 Feb 2016 | Promega Corp.
Easy to use
Luminescent assays
Very easy to use; good alternative to multimode readers for labs doing mostly luminescence assays.
Review Date: 10 Feb 2016 | Promega Corp.
Easy to use and rapid results.
Luciferase assays, fluorescent assays in 96-well plate format
We have used this machine for both luciferase and fluorescent assays in 96-well plate format. The machine is easy to use and protocol addition is very simple. Readings are rapid but reproducible. We recommend this product.
Review Date: 10 Feb 2016 | Promega Corp.
I got great results
Measure cell viability or death in living cells during a drug treatment
it is really very easy to use and it is very sensitive
Review Date: 7 Dec 2015 | Promega Corp.
Cell based assays, protein quantification, biochemical assays
The instrument is super easy to use and really powerful in terms of possible applications.
Review Date: 13 Jul 2015 | Promega Corp.
Reading fluorescence and luminescence on 96 multi well plate
I use GloMax Discover to analyse the effect of compounds on my cells. I have a limited amount of cells, being primary cells so I need high sensitivity and to optimize experiment. With GloMax Discover I can read in same experiment and same well luminescence and fluorescence to analyse viability and cyotoxitcty due to my treatment. The instrument is really very user friendly and it is very sensitive even with low cell amount. I truly recommend it.
Review Date: 31 Mar 2015 | Promega Corp.
This ready-to-use multimode detection system includes: high-performance luminescence, fluorescence, UV-Visible absorbance, BRET and FRET, two-color filtered luminescence and kinetic measurement capabilities.
The GloMax® Discover System is a high-performance multimode detection instrument developed with Promega reagent chemistries to provide a simple means of detecting advanced chemistries. This instrument provides researchers superior luminescence sensitivity and dynamic range for both strong and weak bioluminescence experimental samples, as well as a seamless integration with Promega’s industry leading bioluminescent assays. GloMax® Discover also provides flexible use of filters for fluorescence intensity, BRET, FRET, filtered luminescence and UV-visible absorbance measurements.
The instrument is operated by an integrated Tablet PC, which provides quick and easy navigation through the control options. Exporting your results is made seamless with a variety of options, including exporting to your local data network. The GloMax® Discover software provides the required technical elements of a 21 CFR Part 11-compliant system to be used with the appropriate laboratory workflow.
GloMax® Discover System Features:
- Integrated with Promega Assays - Developed and optimized with Promega cell and gene reporter assays for seamless workflow; you will be up and running faster.
- Easy-to-Use - Simple Tablet PC touch screen navigation with full PC capabilities and a state-of-the-art graphical user interface.
- Superior Performance - Broader dynamic range, better sensitivity and lower well-to-well cross talk for more usable data from your experiment.
- Cost-Effective - Spend less time optimizing.
- Connected to Your Workflow - Use as a standalone instrument or integrate into your high-throughput automated workflow; export data to your laboratory network; enable 21 CFR, Part 11 electronic signature compliance.
Applications:
- Integration with Promega reagent chemistries for detection of fluorescence intensity, BRET, FRET, filtered luminescence and UV-visible absorbance assays.
- Integration into low- and medium-throughput automation workflows.
- Optimization with Promega cell and gene reporter assays.
Multiplexed Measurement of Protein Levels, Transcriptional Activation, and Cell Viability
Cellular stress responses often involve changes in the stability of a critical regulatory protein, followed by downstream modulation of specific transcriptional targets. This application note describes a multiplexed assay of protein level, transcriptional activation, and cell viability in the same well using NanoDLR™ and CellTiter Fluor™ Assays on the GloMax® Discover System. It also demonstrates how multiplexed measurements of protein abundance, gene expression, and cell viability can greatly increase the amount of information obtained from a single sample.
Detection of HIF1α Expression at Physiological Levels Using NanoLuc® Luciferase and the GloMax® Discover System
This application note demonstrates the utility of NanoLuc® Luciferase and the GloMax® Discover System for measuring gene expression at physiologically relevant levels – using hypoxia inducible factor 1 alpha expression (HIF1α) as an experimental system. It also shows that the demonstrate detection with the GloMax® Discover System. It finds that the GloMax® Discover System coupled with the NanoLuc® luciferase technolog
A Flexible Workflow for Automated Bioluminescent Kinase Selectivity Profiling
Kinase profiling is a necessary process to confirm inhibitor selectivity and assess off-target activity. The arduous task of optimizing kinase reactions and maintaining a library of enzymes often results in the outsourcing of kinase profiling activities. This poster demonstrates how ready-to-use Kinase Selectivity Profiling Systems (KSPS) combined with easy-to-use instrumentation and automated data analysis supports a streamlined workflow to enable quick and efficient in-house kinase profiling.
A Homogenous Bioluminescent System for Measuring GTPase, GAP and GEF Activities
GTPases play a major role in various cellular functions such as cell signaling, cell proliferation, cell differentiation, cytoskeleton modulation and cell motility. Deregulation or mutation of these proteins results in serious pathological conditions. Targeting GTPases and their regulators have been challenging due to lack of convenient assays. This poster demonstrates the use of a homogenous bioluminescent assay (GTPase/GAP/GEF-Glo) system to analyze these proteins in a simple, convenient “add-mix-read” format, overcoming the challenges in analyzing activities of GTPases and their regulatory proteins, GTPase Activating Proteins (GAP) and Guanine Nucleotide Exchange Factors (GEF).
Measuring the Output of the CytoTox-Fluor™ Cytotoxicity Assay on the GloMax® Discover System
This application note describes the protocol for measuring fluorescence using the GloMax® Discover System with the CytoTox-Fluor™ Cytotoxicity Assay. The GloMax® Discover System in combination with the CytoTox-Fluor™ Cytotoxicity Assay provides a convenient, rapid and sensitive procedure for determining the number of dead cells in cell populations. Fluorescence correlates with the presence of a distinct protease activity associated with cytotoxicity and loss of membrane integrity.
Measuring the ADCC Reporter Bioassay, Complete Kit (WIL2-S) Signal on the GloMax® Discover System
This application note describes the protocol for measuring luminescence using the GloMax® Discover System with the ADCC Reporter Bioassay Complete Kit (WIL2-S). Antibody-dependent cell-mediated cytotoxicity (ADCC) is a mechanism of action of antibodies through which virus-infected or other diseased cells are targeted for destruction by components of the cell-mediated immune system, such as natural killer cells. The GloMax® Discover System used in conjunction with the ADCC Reporter Bioassay provides an optimized bioluminescent procedure for quantifying biological activity on pathway activation by therapeutic antibody drugs in an ADCC mechanism of action (MOA) assay.
ZEISS LSM 880 With Airyscan Wins Life Science Scientists' Choice Award®
New technology wins prestigious award, presented at AACR 2015
Vote for the Life Science Product of the Year in the Scientists’ Choice Awards!
Don’t miss your chance to win an iPad Air
