Gibco™ CTS™ OpTmizer™ Pro SFM, bag format by Thermo Fisher Scientific

Gibco CTS OpTmizer Pro SFM, no phenol red, is a novel serum-free medium (SFM) developed for the growth and expansion of human T lymphocytes (e.g., CD4+, CD8+, polyclonal, or antigen specific) used in allogeneic cell therapies. This medium improves central memory phenotype and cell growth by shifting the cell’s metabolism. The result is a larger population of central memory cells in a shorter period of time.

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Gibco™ CTS™ OpTmizer™ Pro SFM, bag format

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Benefits

Maintains central memory T cells further into expansion and is well suited for longer workflows (>15 days)
Offers >90% (average) T cell fold expansion (from healthy donors) compared to CTS OpTmizer medium
Modest increases in central memory cells at early stage in expansion protocol result in larger cell yields at harvest
Helps achieve the same number of cells in a shorter duration
Ideally suited to the production of allogeneic therapies

Features

Serum-free and xeno-free
Supports high density cultures in static cultures
New film (Aegis) and bag design allow compatibility with closed systems
Supports T-cell activation using Dynabeads magnetic beads, soluble antibodies, and stimulatory antibody-presenting cell protocols

Increased efficiency and consistence performance

CTS OpTmizer Pro SFM, no phenol red, is serum-free and xeno-free and supports high density cultures in static cultures. It displays consistent performance in the support of T-cell expansion with better central memory phenotype in a shorter time.

Enhanced expansion

CTS OpTmizer Pro SFM, no phenol red, increases the number of central memory cells at an early stage in the expansion process and maintains T-cell functionality.

Enhanced design and compatibility

Use of Thermo Scientific Aegis5-14 Film allows compatibility with closed systems. This film is a five-layer cast film produced in a cGMP facility. The outer layer is a polyester elastomer coextruded with an ethyl vinyl alcohol (EVOH) barrier layer and an ultra-low density polyethylene product contact layer. Aegis5-14 Film is manufactured using no animal derived components.

Simplify your transition into clinical research

The Gibco Cell Therapy Systems (CTS) brand offers a broad array of products for use in cell therapy applications, including media, reagents, growth factors, enzymes, cell selection/expansion reagents, and devices. CTS products deliver:

Reduced burden in qualifying reagents
Appropriate certificates of analysis and origin available
Convenient access to our Drug Master File (DMF)

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