Member since: 2014
Organization: Nova Biostorage Plus, LLC
Application Area: Genomics
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They can either consist of just one application or can include several applications, which can be processed without any user intervention. Starting with just one application, automation of additional applications later on is always possible.
Often, the first step consists of the isolation of DNA or RNA from various samples such as blood, bacteria cultures, cells, tissue or plants. If required, normalization of the isolated products is automated by integration of a plate reader. For low volume samples, PCR set-up or sequencing reaction preparations can also be prepared as a possible next step. With the integration of a cycler, the amplification reactions can be performed on the system without any user intervention. The purification of the products is either done by a filtration step or with magnetic beads. Analysis of DNA or RNA products can be automated by integration of different readers or by placing gels on the deck. For cloning steps (incl. colony picking), heating and cooling modules in different shapes for different plate types are available. If colony picking is required, Hamilton can offer an integrated camera.
Beside these main applications, other genomics methods such as DNA digestion, FTA paper application and cDNA or cRNA synthesis are automated as well.