Custom Cell Engineering by Cell Design Studio® by Merck

Manufacturer Merck
Cell Design Studio® is the cell line engineering service partner you can trust to create customized cellular models for your drug discovery and biomanufacturing needs. With access to state-of-the-art genome editing technology (CRISPR, ZFN, and lentiviral technologies), CDS can generate knockout, knock-in, stable expression, or other modifications in any gene target and virtually any cell line. 


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Custom Cell Engineering by Cell Design Studio®
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Merck aim to solve the toughest problems in the industry. They excel at any modification, any target, and any cell type, including the most challenging cell lines. Their team of PhD Scientists and R&D centric environment allows collaborative communication with scientists, access to Merck's gene editing tools portfolio (CRISPR/Cas9, Zinc Finger Nuclease, Lentivirus), and state-of-the-art technologies and instrumentation. Engineered cell lines can be developed for research and drug discovery, or development with GMP-like documentation for biomanufacturing or batch release assays. With insights and applications across the complete spectrum of development challenges, Cell Design Studio® can help you take your project from research to reality.

Immunotherapy Research:

  • CAR-T Target Reporter Cell Line Generation
  • Solid Tumor Antigen Expression Cell Lines
  • Checkpoint Inhibitor Knockout & Overexpression Cell Lines
  • Therapeutic Antibody Knockout & Overexpression Cell Lines
  • T Cell Receptor Modifications
  • Engineered Cells for Cell/Gene Therapy Evaluation (RUO) prior to MCB Generation
  • Enhancement of Production Cell Lines for RUO
  • Pluripotent Stem Cells & Primary Cells:
  • Isogenic IPS Cell Line Generation and SNP Modifications for Disease Modeling
  • Lineage Tagging and Reporter Cell Lines for Directed Differentiation Protocol Development
  • Safe-harbor Integration of dCas9-based Effectors

Drug Discovery:

  • Reporter Cell Lines for High-Content Analysis and Phenotypic Screening
  • KO/KI Cell Lines for Target ID/Validation
  • Stable Cas9 Cell Lines for CRISPR Screening
  • Stable transgene expression
     

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Custom Cell Engineering by Cell Design Studio® by Merck product image

Custom Cell Engineering by Cell Design Studio®

Manufacturer Merck

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