CYP3A2 is constitutively expressed in male rats and is inducible in both sexes2. CYP3A2 catalyzes the 6beta and 2beta hydroxylation of testosterone. This product is baculovirus-insect cell expressed. With cDNA-expressed rat P450 reductase and human cytochrome b5.
1. J. Biol. Chem., 257:2378 (1982).
2. J. Biol. Chem., 260:7435 (1985).
Available size: 0.5 ml
Representative total protein concentration: 5.0 mg/ml
Catalytic assay: testosterone 6(beta)-hydroxylase activity
Representative activity: 3,600 pmol product/(min x mg protein)