Corning® Supersomes™ P450 Inhibition Kit CYP2C19/CEC, 1/Case by Corning Life Sciences

Kit Components:• CYP2C19 + P450 Reductase + Cytochrome b5• Control: Insect Cell Membrane Protein• Buffer Solution: 0.5 M Potassium Phosphate (pH 7.4), filter sterilized• Stop Solution: 0.5 M Tris Base, filter sterilized• Cofactors: 1.3 mM NADP+, 66 mM MgCl2, and 66 mM Glucose 6-Phosphate• Glucose 6-Phosphate Dehydrogenase: 40 units/mL in 5 mM Sodium Citrate Buffer (pH 7.5)• CEC (3-Cyano-7-Ethoxycoumarin): Fluorescence substrate, 1.5 mg• TCP (Tranylcypromine): CYP2C19 selective positive control i... Read more


Corning® Supersomes™ P450 Inhibition Kit CYP2C19/CEC, 1/Case by Corning Life Sciences product image
Corning® Supersomes™ P450 Inhibition Kit CYP2C19/CEC, 1/Case


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Kit Components:
• CYP2C19 + P450 Reductase + Cytochrome b5
• Control: Insect Cell Membrane Protein
• Buffer Solution: 0.5 M Potassium Phosphate (pH 7.4), filter sterilized
• Stop Solution: 0.5 M Tris Base, filter sterilized
• Cofactors: 1.3 mM NADP+, 66 mM MgCl2, and 66 mM Glucose 6-Phosphate
• Glucose 6-Phosphate Dehydrogenase: 40 units/mL in 5 mM Sodium Citrate Buffer (pH 7.5)
• CEC (3-Cyano-7-Ethoxycoumarin): Fluorescence substrate, 1.5 mg
• TCP (Tranylcypromine): CYP2C19 selective positive control inhibitor, 0.0509 mg
• CHC (3-Cyano-7-Hydroxycoumarin): Metabolite standard (10 uM in water)

Note
• Freeze/thaw stability: This CYP2C19 inhibitor screening kit was subjected to 10 freeze/thaw cycles without a change in IC50 value for tranylcypromine or a significant loss of signal to noise
• # Patent pending
• xx =Actual values can be found on the data sheet accompanying each shipped product

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Corning® Supersomes™ P450 Inhibition Kit CYP2C19/CEC, 1/Case by Corning Life Sciences product image

Corning® Supersomes™ P450 Inhibition Kit CYP2C19/CEC, 1/Case

Manufacturer Corning Life Sciences

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