Member since: 2017
Very easy to use and understand. Up and running in an hour or two. Excellent results.
Application Area: Cell line development
"Allows deposition of a single cell in each well in 5 - 10 minutes with high viability. Such high viability efficiency means far fewer plates needing imaging. For proving and tracing monoclonality, this enables getting all plates in the incubator on day zero."
Cell sorting with imaging and analysis for assurance of monoclonality
The CloneSelect™ Single-Cell Printer™ (SCP) utilizes microfluidics technology and real-time image analysis to sort and deposit single cells into standard microplates. An innovative cartridge, similar to ink-jet printing technology, is used for one-way dispensing. It can print a 96-well plate in 5 to 10 minutes and works with 384-well plates. Five images are captured as cells dispense, providing proof of single-cell isolation.
Sort single cells with efficiency
Sort single cells with higher efficiency (>80%) than limiting dilution and with higher viability than flow sorting (average between 50 – 90% depending on cell conditions).
Capture proof of cell isolation
Capture a sequence of five images as the cell is dispensed, providing image evidence of monoclonality. Wide depth-of-field and 10x magnification ensures image focus 99% of the time.
Differentiate single cells easily
Differentiate quickly between single cells, multi-cell, no cells, and debris with high-resolution imaging with proprietary algorithms. Single cells are plated while unwanted samples are siphoned away.