ChemiSCREEN™ Membrane Preparation Recombinant Human S1P1 Lysophospholipid Receptor by Merck

Manufacturer Merck
EMD Millipore's S1P1 membrane preparations are crude membrane preparations made from our proprietary stable recombinant cell lines to ensure high-level of GPCR surface expression; thus, they are ideal HTS tools for screening of S1P1 interaction with its ligands. The cell line exhibits a calcium response with EC50s of 141 μM for Sphingosine 1-phosphate. The membrane preparations exhibit EC50s of 9.5 μM for Sphingosine 1-phosphate in a GTPγS binding assay.


ChemiSCREEN™ Membrane Preparation Recombinant Human S1P<sub>1</sub> Lysophospholipid Receptor by Merck product image
ChemiSCREEN™ Membrane Preparation Recombinant Human S1P1 Lysophospholipid Receptor

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EMD Millipore's S1P1 membrane preparations are crude membrane preparations made from our proprietary stable recombinant cell lines to ensure high-level of GPCR surface expression; thus, they are ideal HTS tools for screening of S1P1 interaction with its ligands. The cell line exhibits a calcium response with EC50s of 141 μM for Sphingosine 1-phosphate. The membrane preparations exhibit EC50s of 9.5 μM for Sphingosine 1-phosphate in a GTPγS binding assay.

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ChemiSCREEN™ Membrane Preparation Recombinant Human S1P<sub>1</sub> Lysophospholipid Receptor by Merck product image

ChemiSCREEN™ Membrane Preparation Recombinant Human S1P1 Lysophospholipid Receptor

Manufacturer Merck

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