ChemiSCREEN™ Membrane Preparation Recombinant Human mGLU2 Metabotropic Glutamate Receptor by Merck

Manufacturer Merck
Chemicon's mGlu2 membrane preparations are crude membrane preparations made from our proprietary stable recombinant cell lines to ensure high-level of GPCR surface expression; thus, they are ideal HTS tools for screening of mGlu2 interactions with its ligands. The cell line exhibits a calcium response with EC50s of 0.51uM, 5.6uM, and 8.3uM for DCG IV, (2R4R) APDC, and glutamate. The membrane preparations exhibit EC50s of of 0.72uM, 5.07uM, and 6.29uM for DCG IV, (2R4R) APDC, and glutamate in a G... Read more


ChemiSCREEN™ Membrane Preparation Recombinant Human mGLU<sub>2</sub> Metabotropic Glutamate Receptor by Merck product image
ChemiSCREEN™ Membrane Preparation Recombinant Human mGLU2 Metabotropic Glutamate Receptor

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Chemicon's mGlu2 membrane preparations are crude membrane preparations made from our proprietary stable recombinant cell lines to ensure high-level of GPCR surface expression; thus, they are ideal HTS tools for screening of mGlu2 interactions with its ligands. The cell line exhibits a calcium response with EC50s of 0.51uM, 5.6uM, and 8.3uM for DCG IV, (2R4R) APDC, and glutamate. The membrane preparations exhibit EC50s of of 0.72uM, 5.07uM, and 6.29uM for DCG IV, (2R4R) APDC, and glutamate in a GTPγS binding assay.

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ChemiSCREEN™ Membrane Preparation Recombinant Human mGLU<sub>2</sub> Metabotropic Glutamate Receptor by Merck product image

ChemiSCREEN™ Membrane Preparation Recombinant Human mGLU2 Metabotropic Glutamate Receptor

Manufacturer Merck

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