miniDAWN® by Waters | Wyatt Technology

"The Wyatt system is super user-friendly and provides high-quality data for our applications. The upgraded software is pretty good and the HPLC manager makes it very streamlined."

"These instruments are very effective to support analysis on intermediates and drug substances. With these instruments, we have kept achieving high quality and reproducible results. If the users are well trained, these instruments are easy to use and maintain, but highly recommend to follow the procedures of maintenance the vendor suggests, e.g. there are some tricks for cleaning the flow cell. Overall, MALS/RI system is great tool to enable our success in separating large biomolecules and measuring molecular weight and mass."

"The instrument is very easy to use! The touchscreen and ability to control the detector without the need of a separate computer saves time and streamlines the maintenance and care aspect. Any issues that we have had with the system were rapidly resolved by the customer service officials and the local reps."

"The miniDawn is a highly efficient instrument which has proven invaluable in characterization of new metal catalysts. The Wyatt team works with you to allow users to expand their knowledge, especially when inventing new specialized chemicals with no references. Sending the instrument to Wyatt for annual calibration is the most cumbersome task but necessary for such high accuracy and precision when analyzing the unknown."

"We have been using the miniDAWN at our institute (IBCP, CNRS, University Lyon, Lyon, France). We have been 100% happy with this machine, providing us with an easy-to use system. The reliability is excellent and the company has been extremely helpful on many occasions."

"Next generation technology vital for life sciences."

"Great customer service and educational seminars. Dr. Wyatt and his team take time to teach users how to use the unit and self troubleshoot. "

"Awesome customer service, tailored to our needs, toubleshoot our science, innovative, provide teachings and courses."

"This product is very effective and enables high quality results. It is easy to use. I am more than happy to recommend it to others."

"The MALS detector is one of the champions in determining MW of large molecules, what’s fascinating about it is the fact that it could easily differentiate between 10kDa, 25 kDa, 49 kDa, 90.5 kDa with ease with extremely narrow margin of error. The product was delivered to us seem less was with true professionals, the next day the engineer drop by in our lab and installation was done in a flash. Whenever we encountered slight problems, they would always hear us patiently and delivered solutions over telephone, if not done then they would personally visit and rectify. I would highly recommend this detector."

"The instrument is a must have for analysis of protein therapeutics. It gives a huge advantage to typical analytical SEC when used as SEC-MALS mode because it gives you the absolute molecular weight rather than comparing peaks to a standard. This can help avoid misinterpretation of column interactions as aggregation as well as other common mistakes."

"Easy to use software especially if you attend their training classes at Light Scatter University. By far the most superior application to determine molecular weight & oligomeric state of a protein or protein complexes. Customer service respond to your request in a very timely fashion and their excellent professionalism and expertise will be able solve any technical inquires you have."

"Reproducible results. Easy to use and a lot of applications in protein/protein interactions"

"Instrument used to determine the masses and rg of polymers (polyamide-imide) Easy to use instrument and software but difficulty to exploit the data (method of integration, drift baseline ...) and especially hard to understand the conformation plot, for example"

"Our biopolymer laboratory has been using Wyatt instruments, including the miniDawn Treos, for many years. This instrument is configured with FPLC/HPLC third party equipment for SEC analysis. The setup of the instrument is straightforward. I consider the miniDawn Treos a great investment as our Wyatt instruments are running almost every day with reproducible results and absolutely no problems. The Wyatt company always offers excellent customer service and technical support which is a must have item in polymer analysis."

"Yes, I achieve high quality results and I have many papers in which I obtained results by LS. It is very easy to use."

"Excellent equipment. Delivers reproducible and accurate results. Relatively easy operation. Wyatt's support service is quick and attentive."

"Our lab uses the Wyatt instruments (TREOS, QELS and rEX) for molecular weight and Rh measurements with our SEC methods. Training included with the instruments is thorough, and the instruments are easy-to-use after LSU. SEC-MALS is an easy way to determine the online Mw/Rh without adding further methods. Wyatt support reps are quick to reply, and thorough with answers. Would definitely recommend."

"My lab has been using this equipment for the past three years. It is so reliable and easy to use that it is used by all the students. We use it to determine the oligomeric states of our proteins and complexes and have obtained spectacular results with it. It has also completely changed our way of looking at size exclusion chromatography. We use for every single project now. Our best purchase."

"The instrument works very well for the absolute determination of molecular weight of the carbohydrates that we are analyzing, except for the very highest molecular weight fraction (above 10000 kDa). We have some small problems with increasing noise levels over time, which means that the cell needs to be cleaned from time to time, but else that that the setup is working very well. The use of the instrument requires a bit of skill and understanding, but Wyatt's training program does an excellent job in educating the users in this regard. The investment in the miniDAWN TREOS has certainly been a good one for our company."

"The Detector is very easy to operate. The support is fast and attencious."

"Due to the nature of our materials, no chromophore and not RI sensitive enough, we have employed the miniDawn MALS detector in our process. The development of methods was straight forward, validatable, and reproducible. We have now employed this technique in all of our in-process/finished product testing and in our equipment cleaning procedures. We are so impressed with the instruments and the after sales support of our systems we have just completed the purchase and installation of a second set of instruments, the miniDawn and T-rEX."

"Primary application is to verify molecular weights of proteins and aggregates when coupled to SEC. I think the software is very versatile and easy to use. I found using the instrument in batch mode to be extremely tedious and not very informative. I was disappointed since this application did not measure up to my expectations. I found the instrument easy to use and to calibrate and required little maintenance. Probably the most useful was customer support. The reps I spoke to have always been highly knowledgeable and eager to help. "

"High quality instrumentation and excellent customer service. Comprehensive service contract helps keep the instrument in excellent running condition for 10+ years of high volume use. Great software - highly refined and user-friendly. Excellent compatibility with third-party equipment."

"Setup and configuration for use is straightforward. easy to maintain, and generated god and reproducible results "

"Easy to use and >5 years later still turning out useful data"

"This instrument was subtle to use, like for the interpretation of the results but when everything is well understood, all analysis is very clear, reproducible, and verified by other complementary analysis! I strongly recommend this kind of equipment in any Bio-Physical and Bio-Chemistry lab! "

"Excellent product that provides consistent results."

"Costly instrument and high cost of service. very difficult to set the method"

"The miniDAWN TREOS is used in our lab to verify the Mw of our protein projects. The hardware and GUI are simple interfaces, and the Astra software is quite user friendly. Ours has been in service for almost 8 years and still works as if it were brand new. Wyatt continues to provide an unmatched level of support."

"I use this product for Mw and Mn testing for polyurethane, PDMS, Elasteon and R&D samples. It does not require calibration, results are absolute and accurate value based on dn/dc value which can be calculated using Wyatt Optilab ReX and Astra software."

"This instrument has been a great addition to our lab. the customer support is the best around."