Wieslab® Complement Screen (RUO & IVD*)
Wieslab® Complement Screen kit is available as both IVD* and RUO, detects Classical, MBL, and Alternative pathways in human serum samples using ELISA technology with specific detection of C5b-9 for accurate results offering advantages over traditional assays. The RUO is also suitable for primates and porcine samples. It is effective in complement therapeutics evaluation and drug development. *Subject to local registration.
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The Wieslab® Complement system Screen kit is an enzyme immunoassay for the qualitative determination of functional classical, MBL, and alternative complement pathways determination and determination of complement deficiencies in human serum. Non-human primate and swine samples can also be assayed with the Wieslab® Complement system Screen.
The assay combines the specific activation of each pathway with the use of labeled antibodies specific for a neoepitope of the terminal complement complex, C5b-9, produced as the result of complement activation. The amount of C5b-9 generated is proportional to the functional activity of complement pathways.
The Wieslab Complement assays have been published as a useful tool in the evaluation of complement therapeutics, in the clinic, clinical trials, and in drug development.
