Pellicon 3 Cassettes
Advanced, high performance cassettes ideally suited to today's demanding filtration processes.
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Advanced, high-performance cassettes ideal for today’s higher titer therapeutic antibodies as well as the more demanding filtration processes require higher operating pressures, temperatures and caustic cleaning regimes.
Pellicon 3 cassettes with Ultracel membranes are the optimum tangential flow filtration devices for the filtration of monoclonal antibodies and other therapeutic proteins.
Pellicon 3 cassettes with Biomax membranes are the optimum tangential flow filtration devices for the filtration of solutions containing albumin, hormones, vaccines and growth factors.
Specialized Membranes
Pellicon 3 Cassettes are favorites in both laboratory and large-scale production environments and come loaded with your choice of the following leading-edge membranes:
- Ultracel Membranes – designed for the filtration of therapeutic proteins (such as monoclonal antibodies) and recombinant and non-recombinant proteins. The New D screen is optimized for applications that require higher viscosity and concentration applications
- Biomax Membranes – perfect for the filtration of monoclonal antibodies and solutions containing albumin, hormones, vaccines and growth factors.
Benefits
- Rugged & reliable – ideally suited for today’s more demanding filtration processes
- High performance – produces excellent resolution, yields and back-pressure resistance.
- Optimum product recovery – thanks to proven membrane technology
- Void-free technology – leading-edge membranes resolve virtually any separation challenge
- Defect-free, superior adhesion – Ultracel uses composite membranes cast on a microporous substrate
- Automated manufacturing – delivers unbeatable performance, consistency and reliability
- Easy installation & care – simple to install and maintain
Sodium Hydroxide (0.5 N) Compatibility of Pellicon® 3 Cassettes with10 and 30 kD NMWL Ultracel® Composite Membranes
Pellicon 3 cassettes with Millipore’s Ultracel® PLC membranes are tangential flow filtration (TFF) devices for the filtration of monoclonal antibodies and other therapeutic proteins. They have been optimised for today’s higher titer therapeutic antibodies as well as for the more demanding filtration processes that require higher flow rates, operating temperatures and caustic cleaning regimes, enabling consistently high performance. This study demonstrates the ability of Pellicon 3 cassettes with 10 and 30 kD NMWL Ultracel membranes to perform consistently after exposure to 0.5 N NaOH at 50 °C for up to 50 hours.
