iLite® Cell-based Complement Bioassays
Svar specializes in creating cell-based Reporter Gene Assays with iLite® technology for a range of complement applications. This technology offers a precise, sensitive system with luciferase readout, suitable for assessing drug activity for different targets such as C5a, and through Complement-Dependent Cytotoxicity (CDC) activity.
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Our cell-based complement assays offer a new way of studying the complement system. Based on iLite® technology, these assays use a reporter gene system to detect the presence of the complement component for which they were designed. iLite assays offer excellent sensitivity and specificity which ensures that you get accurate results. As an added convenience, all iLite cell lines come assay-ready – no cell culturing is required. This results in a faster workflow and dramatically improved reproducibility and overall performance.
Addressing the analytical gaps in modern therapeutic development
As biopharmaceuticals evolve toward complex modalities like gene therapies and immune-modulating biologics, traditional analytical methods often fall short. Cell-based assays are rising as essential tools but developing robust, context-specific solutions remains challenging.
Discover how tailored cell-based assay strategies can overcome these hurdles and support regulatory-ready data generation. Explore the key challenges and find practical guidance to help advance your analytical capabilities for next-generation therapeutic development.
A guide to complement therapeutics for drug development professionals
This comprehensive eBook covers the fundamental aspects of complement therapeutics, ranging from the basics of the complement system to the challenges and opportunities in drug development.
It aims to provide practical insights into the development process, regulatory considerations, and the broader landscape of complement-targeted therapies. The inclusion of case studies, editorial articles, and scientific material is intended to add depth and relevance for professionals in the pharmaceutical industry.
Download to:
- Discover an introduction of the complement system
- Gain an understanding of the fundamental components of complement
- Explore the complement’s prospective therapeutic targets
- Engage with in-depth discussions on biomarkers, monoclonal antibodies (mAbs), and aptamers
- Understand the significance of complement within novel modalities like gene therapy
