ResourceDrug Discovery & Development
A guide to complement therapeutics for drug development professionals
31 Oct 2024
Dora Wells
Clinical Content Editor
This comprehensive eBook covers the fundamental aspects of complement therapeutics, ranging from the basics of the complement system to the challenges and opportunities in drug development.
It aims to provide practical insights into the development process, regulatory considerations, and the broader landscape of complement-targeted therapies. The inclusion of case studies, editorial articles, and scientific material is intended to add depth and relevance for professionals in the pharmaceutical industry.
Download to:
- Discover an introduction of the complement system
- Gain an understanding of the fundamental components of complement
- Explore the complement’s prospective therapeutic targets
- Engage with in-depth discussions on biomarkers, monoclonal antibodies (mAbs), and aptamers
- Understand the significance of complement within novel modalities like gene therapy
Links
Tags
BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Therapeutic DrugsDrug DevelopmentDrug development refers to the process of bringing a new drug to market.Gene TherapyGene therapy is a technique that modifies or replaces genes within an individual's cells to treat or prevent diseases. This approach holds potential for curing genetic disorders, cancers, and certain viral infections. Advances in gene editing technologies like CRISPR are driving the growth of gene therapy. Explore gene therapy tools and technologies in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.
