GloMelt™ 2.0 Thermal Shift Protein Stability Kit
A high-throughput fluorescence-based assay for protein stability screening with higher tolerance for detergents and other protein additives compared to commonly used Thermal Shift dyes.
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The GloMelt™ 2.0 Thermal Shift Protein Stability Kit is a high-throughput and cost efficient method for screening ligand binding of molecules or identifying stability changes from protein modifications. The assay measures protein thermal stability, also known as a thermal shift assay, Protein Thermal Shift™, differential scanning fluorimetry, or Thermofluor assay.
Applications
- A high-throughput method for sample screening via protein thermal stability
- Screen molecules (e.g. drug candidates, antibodies) for ligand binding
- Identify protein stability changes from point mutations or other modifications
Features
- Higher tolerance for detergents and other additives compared to commonly used thermal shift dyes
- Green fluorescence optimal for qPCR instruments and ROX normalization
- Suitable for wide pH range, low reaction volumes, or low protein concentrations
- Highly soluble and stable in aqueous buffers
- Includes recombinant mouse IgG1 control protein — ideal for therapeutic antibody research.
- Perfect for high-throughput assays with low volumes and protein concentrations.
GloMelt™ Thermal Shift Protein Stability Kit 2.0 #33027-1
GloMelt™ Thermal Shift Protein Stability Kit 2.0 #33027-T
GloMelt™ Thermal Shift Protein Stability Kit 2.0 with ROX #33028-1
GloMelt™ Thermal Shift Protein Stability Kit 2.0 with ROX #33028-T
