Biotage® Extrahera™ HV-5000
Automated sample preparation workstation for high volume samples
The Biotage® Extrahera™ HV-5000, is a GLP-capable, automated sample preparation workstation dedicated to column-based sample prep with support for classical 3-, 6-, 10- and 15-mL SPE and SLE column consumable formats.
Automated clean up of pesticides in spinach using cSPE for QuEChERS
This application note presents an automated workflow for pesticide residue analysis in spinach using QuEChERS extraction followed by column-based solid phase extraction clean‑up. The use of ISOLUTE® cSPE columns enables efficient sample purification with high recoveries and reproducibility, while automation increases throughput and reduces manual error. Results demonstrate reliable multi-residue analysis across a wide range of compounds using LC‑MS/MS.
Food analysis sample preparation workflows from Biotage
This brochure outlines Biotage’s end‑to‑end sample preparation solutions for food analysis, covering workflows from homogenization and extraction through to clean‑up and evaporation. It highlights technologies including SPE, QuEChERS, and automated processing systems designed to improve analyte recovery, reproducibility, and throughput across applications such as pesticide, mycotoxin, and acrylamide analysis.
Automated extraction of acrylamide from instant coffee using Extrahera HV 5000
This application note describes an automated solid phase extraction workflow for quantifying acrylamide in instant coffee using the Extrahera™ HV‑5000 system from Biotage. The method combines multimode and ENV+ SPE columns to deliver high recovery and reproducibility, supporting sensitive LC‑MS/MS analysis. Designed in line with EN 16618:2015, the approach enables efficient, high‑throughput sample preparation for food safety testing.
Guide to environmental applications using the Biotage Extrahera HV-5000
There are very few techniques that can reliably analyze raw samples. Components in the sample matrix frequently interfere with analysis and mask analytes, especially in chromatographic analyses. The solution is to perform sample preparation that can bring significant benefits to the analytical laboratory. Download this application note to see how the Biotage® Extrahera™ HV-5000 is used in sample preparation.
Guide to environmental applications using Biotage Extrahera HV-5000
There are very few techniques that can reliably analyze raw samples. Components in the sample matrix frequently interfere with analysis and mask analytes, especially in chromatographic analyses. The solution is to perform sample preparation that can bring significant benefits to the analytical laboratory. Download this application note to find a multitude of applications for the Extrahera™ HV-5000, including tips and tricks for method optimization.





















