Beacon® Optofluidic System
Understand the Life of Single Cells. The Beacon system unites optics, fluidics, and imaging to deliver high‑parameter, real‑time functional analysis of up to 60,000 live single cells. With automated scalability and downstream recovery, it accelerates therapeutic antibody discovery, vaccine development, immune profiling, cell therapy, and cell line development.
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The Beacon optofluidic system revolutionizes single cell research by integrating advanced optics, fluidics, and imaging to deliver large-scale, high-parameter, real-time functional characterization of live single cells. Unlock unprecedented insights in therapeutic antibody discovery, AI-driven antibody engineering, vaccine development, cell line development, and cell therapy innovation—all with unparalleled automation and speed.
The Beacon system accelerates large scale discoveries in antibody development, vaccine development, immune monitoring, cell therapy, and cell line development. It is an essential tool for biopharma therapeutic antibody discovery groups, autoantibody academic research, and top-tier CROs or CDMOs advancing next-generation drug discovery.
Key Benefits:
- Exquisite Control – Build your own single cell experiments with unparalleled precision
- Highest Parameters on Chip – Conduct real-time imaging for serial multi-modal analysis on the same live cells
- Infinite Possibilities off Chip – Identify and recover high-value cells to link on-chip phenotypic data with downstream sequencing
- Automated Scalability – Analyze 500 to 60,000 single cells enabling analysis of precious clinical samples or performing high throughput screening
Key Applications:
- Antibody Discovery
- Vaccine Response Profiling
- Cell Line Development
- T Cell Profiling and TCR/CAR Discovery
- Tumor-Infiltrating Lymphocyte (TIL) Characterization
- Cell Therapy Development and Validation
- Translational Biomarker Discovery
Ready to See What's Possible?
Talk to a Bruker specialist to explore how live single-cell functional analysis and the Beacon platform can elevate your research.
Beacon Optofluidic System
In this poster, Berkeley Lights presents its Beacon Optofluidic System for antibody discovery, cell line development, and cell therapy development.
Berkeley Lights: Antibody discovery
Here, Berkeley Lights presents its antibody discovery workflow.
Opto CLD: The new standard for quality, capacity, and speed in cell line development
Here, Berkeley Lights presents its workflow for cell line development.
Berkeley Lights: Cell line development
Discover Berkeley Lights' workflow for cell line development.
FDA-accepted monoclonality assurance on the Beacon Optofluidic System for cell line development
In this application note, Berkeley Lights presents its Beacon® Optofluidic System for cell line development.
Rapid generation of production cell lines with superior titers and >99% monoclonality for complex antibody molecules
In this poster, Berkeley Lights presents how its Beacon Optofluidics Platform was utilized for the rapid generation of production cell lines with superior titers and >99% monoclonality for complex antibody molecules.
How to get to market faster with Opto cell line development
In this datasheet from Berkeley Lights, discover how to get to market faster with Opto™ cell line development.
Catalent Biologics on cell line development
Here, Catalent Biologics describe how it utilized the Beacon® optofluidic system from Berkeley Lights for cell line development.
Abveris on antibody discovery
Here, Abveris describes how it utilized the Beacon® optofluidic system from Berkeley Lights for antibody discovery.
Succeed against difficult targets with the Opto Plasma B discovery workflow on the Beacon System
Discover how you can get to the clinic faster by accelerating discovery campaigns, finding functional antibodies in one day, and eliminating non-functional hits sooner, with the Beacon® System from Berkeley Lights.
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Beacon® Discovery™ Optofluidic System
Bruker Cellular AnalysisLive Single Cells. Deepest Functional Insights. Beacon Discovery enables real‑time, multimodal functional analysis of thousands of live single cells, linking dynamic assays to sequencing from the same cell. Its compact, cost‑effective platform supports T‑cell profiling, cell therapy development, and antibody discovery.