Application Note: Extending the capabilities of the BioAccord LC-MS System with a streamlined workflow for compliant-ready Multi-Attribute Method (MAM)
22 October 2020

In this application note, Waters discusses the key elements of the new peptide Multi-Attribute Method (MAM) workflow that extend the capabilities of the BioAccord LC-MS System coupled with the novel waters_connect informatics platform. This application note demonstrates the benefits of this new MAM workflow by addressing the challenges in implementing a routine MAM workflow; demonstrating MAM reproducibility and new peak detection capabilities; and by detailing the process for importing attributes for MAM from multiple biotherapeutics characterization platforms