PDX dispatch: Acute myeloid leukemia PDX models

Acute myeloid leukemia (AML) is the most common type of acute leukemia in adults, characterized by chromosomal abnormalities and gene mutations. AML develops through the gradual accumulation of mutations.

Explore how Crown Bioscience has developed a series of AML PDX tumor models that house a variety of disease subtypes and genetic features to support preclinical evaluation of new therapies or combination therapies, and a better understanding of resistance mechanisms.