NGS analysis of hereditary cancer predispositions at the Laboratory of Molecular Genetics, Jihlava Hospital

Explore how the Laboratory of Molecular Genetics at Jihlava Hospital, Czech Republic is utilizing the Agilent 4150 TapeStation system to streamline its NGS workflow, ensuring that only high-quality samples are sequenced.

The team is working to validate an NGS method designed to analyze hereditary predispositions to various cancers, including breast and colon. Their workflow involves isolating DNA from blood and buccal swab samples, with DNA concentration measured post-isolation with a fluorometer. Discover how the lab uses the TapeStation system at two stages, during library prep and before sequencing to assess the quality and quantity of their libraries prior to pooling.