IVT mRNA encapsulation efficiency assessment using Agilent Fragment Analyzer systems

Explore the Agilent Fragment Analyzer systems and discover how they can perform both quantitative and qualitative nucleic acid analysis using parallel capillary electrophoresis, and are routinely used in the characterization of in vitro transcribed (IVT) mRNA drug substance (DS) and drug product (DP). Critical quality attributes (CQAs) commonly assessed with the systems include integrity, size, and purity. The systems can also be used to streamline the IVT mRNA CQA workflow, consolidating essential tests for characterizing IVT mRNA onto one platform.