Spot the Difference: What Causes Variability in Flow-Injection, Dried Blood Spot Analysis, and What You Can Do About It
13 Dec 2018

Tandem mass spectrometry is the detection method of choice when analytical specificity and speed of analysis is needed. Flow-injection analysis tandem mass spectrometry (FIA-MS/MS) enables the rapid and multiplexed screening of compounds, in a single injection. When FIA takes the place of liquid chromatography separations, and we choose internal standardization over multi-point calibration with matrix-based standards, what else should we do to ensure our data is of the very highest quality, as demanded in a clinical setting?

It is important we understand how sample preparation, analytical methods and instrument settings can influence the end result. In having this knowledge, we can address the causes of between- and within-laboratory variation in FIA-MS/MS methods.

This webinar aims to illustrate some of the factors which can influence variability in FIA-MS/MS data, and to provide the audience with ideas for designing system suitability testing procedures to identify sample and instrument-issues before they impact service.

Key learning objectives:

  • The benefits and limitations of flow injection analysis
  • How instrument and sample factors can contribute to variability between systems
  • How to design a system suitability verification procedure to spot system issues before they affect performance
Who should attend?
Laboratory technologists, lab scientists, lab physicians, scientists and researchers who employ flow injection mass spectrometry in routine or research applications

All webinar participants can download a certificate of attendance, with a learning outcomes summary document for continuing education purposes.

Waters