Advancing oral drug development with in vitro dissolution and absorption tools

June 9, 2025 16:00 BST / 17:00 CEST / 11:00 EDT / 08:00 PDT

Effective absorption and therapeutic performance are essential to the success of oral small molecule drugs. In order to achieve this, understanding key biopharmaceutical properties such as solubility, dissolution, and membrane permeability are crucial for optimization as these factors can influence bioavailability and overall clinical efficacy.

Join Karl Box, Chief Scientific Officer at Pion Inc, as he explores innovative in vitro techniques that can help characterize key biopharmaceutical properties — enabling better decision-making from early discovery through to formulation optimization.

Designed for scientists and formulation teams, this exclusive webinar will highlight practical approaches to evaluating oral drug performance using dynamic dissolution and absorption models. Whether you are working on preclinical candidates or refining final dosage forms, gain insight into how real-time in vitro testing can be used to identify formulation risks early, troubleshoot challenges, and support a more efficient development process, to enhance the predictability and success of oral drug development.

Key learning objectives

  • Understand how to apply small-scale and biorelevant dissolution testing to support formulation strategy.
  • Explore tools and workflows for assessing supersaturation/precipitation and excipient selection.
  • Gain insights into how in vitro data can guide risk assessment and improve developability profiling.
  • Learn how to predict oral absorption (Fa%) and assign the BCS Class of your compound.

Who should attend?

  • Pharmaceutical scientists involved in drug development and formulation.
  • Preclinical development teams looking to improve biopharmaceutic assessments.
  • Anyone interested in enhancing their understanding of oral absorption and developability assessment using in vitro methods.
  • R&D professionals interested in in vivo predictive tools.

Certificate of attendance

If you attend the live webinar, you will automatically receive a certificate of attendance, including a learning outcomes summary, for continuing education purposes.

If you view the on-demand webinar, you can request a certificate of attendance by emailing editor@selectscience.net.

Speakers

Karl Box
Karl Box
Chief Scientific Officer, Pion Inc.

Karl Box has served as Chief Scientific Officer (Europe) at Pion (UK) since 2020. He is involved in scientific and chemistry related functions within the company, as well as supporting commercial activities and business development. His expertise is in the field of physicochemical measurements, where he has forged a successful career in the development of new instrumentation and assays for supporting drug discovery and development.

Moderator

Olivia Long
Olivia Long
Editorial Team, SelectScience

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