Rainbow R6 Multi-channel fiber optic UV-VIS Spectrophotometer
Rainbow is an in-situ, fiber optic probe-based, concentration monitor that measures concentration and changes in concentration in real-time without the need for sampling.
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It can be integrated with various dissolution and flux test stations and used to assess solubility, dissolution rate, permeability, supersaturation/precipitation with easy data collection and interpretation.
Benefits:
- Real-time concentration data is provided for all 8 channels.
- 5 different advanced mathematical approaches to deal with turbidity or other disturbances in the spectrum.
- It's Green! No filters, HPLC vials, columns, or eluents. Everything is done in your experiment vessel.
- No separation is needed! Multiple mathematical ways to measure 2-3(-4) absorbing components in the vessel, all in real-time.
- Direct measurements in complex or biorelevant media, even with media conversion.
- Automated data processing to find a reliable way of data refinement
- Data exports to common platforms or to Pion Predictor Software for data processing and reporting.
The Rainbow R6 is the core technology in Pion’s portfolio of dissolution solutions for:
- Dissolution testing
- Drug solubility
- Dissolution monitoring - just add a small volume dissolution tester to your
Rainbow R6:
- MicroDISS - small volumes of 2- 20 ml
- MiniDISS - biorelevant volumes of 100-250 ml
- Absorption and Flux assays - just add FLUX apparatus to your Rainbow R6:
- MicroFLUX using only several milligrams of sample for early-stage development where sample is limited
- BioFLUX at biorelevant volumes (200-250mL) for late stage formulation development
- MacroFLUX for a 900mL vessel of a USP II apparatus designed for use in formulation development based on standard USP dissolution setups
Advancing oral drug development with in vitro dissolution and absorption tools
June 9, 2025 16:00 BST / 17:00 CEST / 11:00 EDT / 08:00 PDT
Effective absorption and therapeutic performance are essential to the success of oral small molecule drugs. In order to achieve this, understanding key biopharmaceutical properties such as solubility, dissolution, and membrane permeability are crucial for optimization as these factors can influence bioavailability and overall clinical efficacy.
Join Karl Box, Chief Scientific Officer at Pion Inc, as he explores innovative in vitro techniques that can help characterize key biopharmaceutical properties — enabling better decision-making from early discovery through to formulation optimization.
Designed for scientists and formulation teams, this exclusive webinar will highlight practical approaches to evaluating oral drug performance using dynamic dissolution and absorption models. Whether you are working on preclinical candidates or refining final dosage forms, gain insight into how real-time in vitro testing can be used to identify formulation risks early, troubleshoot challenges, and support a more efficient development process, to enhance the predictability and success of oral drug development.
Key learning objectives
- Understand how to apply small-scale and biorelevant dissolution testing to support formulation strategy.
- Explore tools and workflows for assessing supersaturation/precipitation and excipient selection.
- Gain insights into how in vitro data can guide risk assessment and improve developability profiling.
- Learn how to predict oral absorption (Fa%) and assign the BCS Class of your compound.
Who should attend?
- Pharmaceutical scientists involved in drug development and formulation.
- Preclinical development teams looking to improve biopharmaceutic assessments.
- Anyone interested in enhancing their understanding of oral absorption and developability assessment using in vitro methods.
- R&D professionals interested in in vivo predictive tools.
Certificate of attendance
If you attend the live webinar, you will automatically receive a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
If you view the on-demand webinar, you can request a certificate of attendance by emailing editor@selectscience.net.
