MRD workshop at AMP 2025 on tumor-agnostic testing and standardization challenges

13 May 2026
MRD workshop at AMP 2025 on tumor-agnostic testing and standardization challenges

This expert panel discussion that took place at the Association for Molecular Pathology (AMP) 2025 Annual Meeting & Expo, explores current advances and future challenges in minimal residual disease (MRD) testing using liquid biopsy technologies. Featuring leaders from academia, industry, and clinical diagnostics, the conversation highlights progress in detecting circulating tumor DNA at extremely low levels, alongside the need for improved sensitivity, specificity, and standardization.

The panel examines emerging approaches such as tumor‑naive MRD testing, multi‑omics integration, including epigenetics and fragmentomics, and the growing role of AI and large datasets in improving assay performance. Key topics also include clinical validation, regulatory challenges, and the potential of MRD testing to enable earlier intervention and more personalized cancer treatment.

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LGC Diagnostics & Genomics - SeraCare Clinical Diagnostics

LGC Clinical Diagnostics & Genomics

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At LGC Diagnostics & Genomics, we drive scientific progress by making our trusted life science solutions both simpler and more innovative.

Partnering with our customers to provide a portfolio of cutting-edge life science tools that diagnose, treat and feed our growing population, delivering on our core mission of Science for a Safer World.

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SeraCare Clinical Diagnostics

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Quality Controls, Reference Materials, Biological Materials, reagent components

Empower your results and challenge your methods with SeraCare’s ACCURUN® molecular and serology controls and reference materials. ACCURUN controls and reference materials are whole-cell or whole-organism external controls that help you monitor all aspects of your molecular or serology testing methods and provide additional confidence in your laboratory test results. A well-designed QC program can help you avoid costly false-negative or false-positive results.

Seraseq® next-generation sequencing (NGS) reference materials enable the promise of precision medicine by supporting NGS assay development and validation in analyzing actionable and challenging variants in patient samples. Using innovative technologies, SeraCare designs and manufactures a comprehensive portfolio of highly multiplexed patient-like reference materials used by assay developers and clinical laboratories to ensure consistency, reproducibility, and confidence of oncology and genomic health assays.

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Epigenetic AnalysisEpigenetic analysis products are used to study heritable phenotype changes that do not alter the DNA sequence, such as DNA modifications affecting gene activity. Determine whether genes have been methylated with DNA methylation quantification kits or methylation microarrays. Assess epigenetic regulation with histone modification kits or ChIP-on-chip microarrays. Kits are also available for bisulfite conversion and amplification of your samples, as well as epigenomic library preparation kits for next-generation sequencing (NGS). Find the best epigenetic products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cancer DiagnosticsThere are a wide variety of diagnostic tests for cancer available, and this range continues to expand as our knowledge of cancer improves. Current diagnostic methods include biopsy, imaging and blood tests for known biomarkers. New methods in research development include liquid biopsies and cancer breathalyzers.Liquid BiopsiesLiquid biopsies are non-invasive tests used to detect cancer and other diseases by analyzing blood or other bodily fluids. This technique is gaining popularity for early detection, monitoring treatment response, and detecting minimal residual disease. Explore liquid biopsy solutions in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Precision MedicinePrecision medicine refers to the idea of customized healthcare, where medical decisions and treatments are tailored to the individual patient. Molecular diagnostics, companion diagnostics and Next Generation Sequencing (NGS) play a pivotal role in this approach. GenomicsGenomics is the study of genomes, focusing on the sequencing, analysis, and interpretation of genetic material. It is key in understanding genetic diseases, evolutionary biology, and personalized medicine. Techniques like next-generation sequencing (NGS) are commonly used in genomics research. Browse our peer-reviewed product directory to find the best genomics tools, compare products, check reviews, and get pricing directly from manufacturers.